Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 4358577..4359361 Replicon chromosome
Accession NZ_CP024676
Organism Citrobacter pasteurii strain UMH17

Toxin (Protein)


Gene name TacT2 Uniprot ID -
Locus tag CUC49_RS21245 Protein ID WP_121585356.1
Coordinates 4358867..4359361 (+) Length 165 a.a.

Antitoxin (Protein)


Gene name TacA2 Uniprot ID -
Locus tag CUC49_RS21240 Protein ID WP_121585355.1
Coordinates 4358577..4358870 (+) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CUC49_RS21235 4357833..4358006 - 174 Protein_4014 molybdopterin-guanine dinucleotide biosynthesis protein B -
CUC49_RS21240 4358577..4358870 + 294 WP_121585355.1 DUF1778 domain-containing protein Antitoxin
CUC49_RS21245 4358867..4359361 + 495 WP_121585356.1 GNAT family N-acetyltransferase Toxin
CUC49_RS21250 4359423..4360121 + 699 WP_121585357.1 hypothetical protein -
CUC49_RS21255 4360108..4361949 - 1842 WP_121585358.1 hypothetical protein -
CUC49_RS21260 4361946..4363856 - 1911 WP_121585359.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(44-144)

Antitoxin

Vibrio phage ICP1, Orf50

(14-88)


Sequences

Toxin        


Download         Length: 165 a.a.        Molecular weight: 17845.71 Da        Isoelectric Point: 8.5113

>T88277 WP_121585356.1 NZ_CP024676:4358867-4359361 [Citrobacter pasteurii]
MISAPEPLHAGHVLTSFCCGVDSMDNWLKQRAMKNQVTGASRTFVCCDNNSKVLAYYSLASSAVTTNTAPGRFRRNMPDP
IPVVVLGRLAVDQSLRGRGIGRALVRDAGLRVIQVAETIGIRGMLVHALSDEAREFYLRVGFEPSPMDSMMLMVTLGDLV
GSFQ

Download         Length: 495 bp

>T88277 NZ_CP024676:4358867-4359361 [Citrobacter pasteurii]
ATGATTTCCGCTCCTGAGCCTCTCCACGCCGGGCATGTTTTGACTTCATTTTGCTGCGGCGTGGATTCTATGGATAACTG
GCTGAAACAGCGGGCGATGAAAAATCAGGTCACAGGCGCATCCCGTACCTTTGTTTGCTGCGACAATAATTCTAAGGTAC
TGGCGTATTACTCGCTGGCGTCCAGCGCTGTAACAACAAACACCGCCCCCGGACGTTTTCGCCGCAATATGCCTGACCCG
ATCCCGGTTGTGGTGCTGGGACGTCTGGCCGTAGATCAATCTCTGCGTGGTCGGGGCATCGGGCGAGCGCTGGTGCGAGA
TGCCGGACTACGGGTGATTCAGGTGGCGGAGACTATCGGCATTCGCGGGATGCTGGTTCACGCATTGTCTGATGAAGCGC
GGGAGTTCTACCTGCGGGTGGGGTTTGAGCCGTCTCCGATGGATTCAATGATGCTGATGGTGACGTTGGGGGATTTGGTG
GGGAGTTTTCAGTAA

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10884.45 Da        Isoelectric Point: 9.8590

>AT88277 WP_121585355.1 NZ_CP024676:4358577-4358870 [Citrobacter pasteurii]
MPAANSLSIKRETLNLRIKPAERDLIDRAAKARGKNRTDFVLEAARAAAEETLIEQRIIMADPDAYQAFLARLDQAPAPN
EALRKTMQTPAPWEQNK

Download         Length: 294 bp

>AT88277 NZ_CP024676:4358577-4358870 [Citrobacter pasteurii]
ATGCCAGCCGCAAATAGCCTGTCTATAAAGCGCGAAACACTTAACCTGCGCATCAAACCTGCCGAGCGCGATCTTATCGA
TCGGGCAGCGAAGGCCAGAGGAAAAAATCGCACGGATTTCGTGCTGGAAGCCGCTCGCGCAGCCGCAGAGGAAACGTTGA
TTGAACAGCGTATCATTATGGCCGATCCCGATGCTTATCAGGCATTTCTCGCCCGCCTCGATCAGGCTCCTGCACCTAAT
GAGGCACTGCGTAAAACCATGCAGACCCCTGCGCCGTGGGAACAGAATAAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References