Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1993501..1993711 Replicon chromosome
Accession NZ_CP024676
Organism Citrobacter pasteurii strain UMH17

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1993506..1993609 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1993501..1993711 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CUC49_RS09585 1988718..1988954 + 237 WP_101742234.1 DUF1480 family protein -
CUC49_RS09590 1988982..1990220 - 1239 WP_082759583.1 MFS transporter -
CUC49_RS09595 1990290..1991207 + 918 WP_121584746.1 LysR family transcriptional regulator -
CUC49_RS09600 1991280..1991471 + 192 WP_048211387.1 YebW family protein -
CUC49_RS09605 1991472..1992113 - 642 WP_061068066.1 protein-serine/threonine phosphatase -
CUC49_RS09610 1992359..1993141 - 783 WP_048211385.1 HNH endonuclease -
- 1993501..1993711 + 211 - - Antitoxin
- 1993506..1993609 - 104 - - Toxin
CUC49_RS09620 1993765..1994103 - 339 WP_061068068.1 YebY family protein -
CUC49_RS09625 1994120..1994992 - 873 WP_116359890.1 copper homeostasis membrane protein CopD -
CUC49_RS09630 1994996..1995370 - 375 WP_044711069.1 CopC domain-containing protein YobA -
CUC49_RS09635 1995513..1995743 + 231 WP_005120732.1 DNA polymerase III subunit theta -
CUC49_RS09640 1995850..1996506 + 657 WP_061068070.1 carbon-nitrogen hydrolase family protein -
CUC49_RS09645 1996529..1997191 + 663 WP_061068071.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 1987196..1999272 12076


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T88264 NZ_CP024676:c1993609-1993506 [Citrobacter pasteurii]
GGCAGGGTAACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 211 bp

>AT88264 NZ_CP024676:1993501-1993711 [Citrobacter pasteurii]
CACATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTT
GGCATTAATGCAGGCTAAGTTACCCTGCCATTTAAGAATAGATGACAGCGCCAGGTTTTCCAGTCCGCGACTAAAGTGGT
CTGAAAAAAAGGGAGATTGTCACTCGCTACAATGTAAAAACCGCAAGTTCT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References