Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2145542..2145683 Replicon chromosome
Accession NZ_CP024672
Organism Citrobacter freundii strain HM38

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2145545..2145648 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2145542..2145683 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CUC52_RS24330 2140818..2141030 + 213 WP_153070801.1 hypothetical protein -
CUC52_RS10530 2141092..2141418 + 327 WP_060855149.1 Rrf2 family transcriptional regulator -
CUC52_RS10535 2141560..2144031 + 2472 WP_060855113.1 exonuclease -
CUC52_RS10540 2144095..2144355 + 261 WP_072211989.1 hypothetical protein -
CUC52_RS10545 2144333..2145412 + 1080 WP_016150458.1 phage integrase Arm DNA-binding domain-containing protein -
- 2145542..2145683 + 142 - - Antitoxin
- 2145545..2145648 - 104 - - Toxin
CUC52_RS10550 2145804..2146142 - 339 WP_060855112.1 YebY family protein -
CUC52_RS10555 2146163..2147035 - 873 WP_060855111.1 copper homeostasis membrane protein CopD -
CUC52_RS10560 2147039..2147413 - 375 WP_003034928.1 CopC domain-containing protein YobA -
CUC52_RS10565 2147557..2147787 + 231 WP_003034925.1 DNA polymerase III subunit theta -
CUC52_RS10570 2147894..2148550 + 657 WP_060855110.1 carbon-nitrogen hydrolase family protein -
CUC52_RS10575 2148574..2149236 + 663 WP_003833802.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2090034..2167378 77344


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T88216 NZ_CP024672:c2145648-2145545 [Citrobacter freundii]
GGCAGGGTAACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 142 bp

>AT88216 NZ_CP024672:2145542-2145683 [Citrobacter freundii]
GATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGG
CATTAATGCAGGCTAAGTTACCCTGCCATTTAAGAATAGATGACAGCGCCAGGTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References