Detailed information of TA system TA088146

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/ParE-RelB
• Location: 5605986..5606511
• Replicon: chromosome
• Accession: NZ_CP024646
• Organism: Pseudomonas syringae isolate inb918

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: CT157_RS25610
• Protein ID: WP_127800128.1
• Coordinates: 5606215..5606511 (+)
• Length: 99 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: CT157_RS25605
• Protein ID: WP_085608779.1
• Coordinates: 5605986..5606225 (+)
• Length: 80 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
CT157_RS25580	5601769..5602230	+	462	WP_007958617.1	GNAT family N-acetyltransferase	-
CT157_RS25585	5602458..5603108	+	651	WP_085608776.1	DedA family protein	-
CT157_RS25590	5603113..5603925	+	813	WP_127800124.1	zinc-dependent peptidase	-
CT157_RS25595	5604040..5604567	+	528	WP_007990564.1	inorganic diphosphatase	-
CT157_RS25600	5604789..5605529	+	741	WP_127800126.1	helix-turn-helix transcriptional regulator	-
CT157_RS25605	5605986..5606225	+	240	WP_085608779.1	type II toxin-antitoxin system RelB/DinJ family antitoxin	Antitoxin
CT157_RS25610	5606215..5606511	+	297	WP_127800128.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
CT157_RS25615	5606571..5607383	-	813	WP_085608781.1	DUF2135 domain-containing protein	-
CT157_RS25620	5607387..5609006	-	1620	WP_127800130.1	DUF2300 domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (5-84)

Antitoxin

• RelB antitoxin/Antitoxin DinJ (1-79)

Sequences

Toxin

Protein

• Length: 99 a.a.
• Molecular weight: 11526.33 Da
• Isoelectric Point: 9.3637

>T88146 WP_127800128.1 NZ_CP024646:5606215-5606511 [Pseudomonas syringae]
MTYNLEFDRRALKEWNKLGDTIREQFKKKLAEVLENPRIEANKLRELPDCYKVKLKSAGYRLIYQVIDHEIVVFVVAIGK
REREAAYDAALDRLSSQP

Nucleotide

• Length: 297 bp

>T88146 NZ_CP024646:5606215-5606511 [Pseudomonas syringae]
ATGACCTATAACCTCGAGTTTGATCGTCGTGCATTAAAGGAATGGAACAAGCTGGGCGATACGATTCGCGAGCAGTTCAA
AAAGAAACTCGCCGAGGTTCTCGAAAATCCTCGCATAGAAGCCAACAAGCTTCGCGAGCTGCCAGATTGTTACAAGGTGA
AGCTGAAAAGCGCTGGGTATCGCCTGATTTATCAGGTGATTGATCACGAAATTGTGGTGTTCGTAGTCGCTATCGGAAAG
AGAGAGCGAGAGGCGGCTTATGACGCTGCACTGGATCGATTGTCGTCCCAACCCTGA

Antitoxin

Protein

• Length: 80 a.a.
• Molecular weight: 8821.23 Da
• Isoelectric Point: 4.8146

>AT88146 WP_085608779.1 NZ_CP024646:5605986-5606225 [Pseudomonas syringae]
MASINIRIDDELKKRAFAELEKLGLSPSELLRQTLQYVADRGKLPFKAALLSEEDEALIAVVTERLAAPQRVKVSLDDL

Nucleotide

• Length: 240 bp

>AT88146 NZ_CP024646:5605986-5606225 [Pseudomonas syringae]
ATGGCATCCATCAATATTCGGATCGACGACGAACTGAAAAAACGCGCCTTCGCAGAGCTGGAAAAGCTGGGGCTTTCGCC
CTCAGAGCTTCTGCGCCAAACGCTTCAATACGTCGCGGACCGAGGCAAATTGCCCTTCAAAGCGGCATTGCTCAGTGAAG
AGGATGAAGCGCTTATCGCCGTGGTCACTGAACGCCTTGCCGCTCCTCAGCGAGTCAAGGTAAGTCTGGATGACCTATAA