Detailed information of TA system TA088145

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relE-yefM/YoeB-YefM
• Location: 5210717..5211222
• Replicon: chromosome
• Accession: NZ_CP024646
• Organism: Pseudomonas syringae isolate inb918

Toxin (Protein)

• Gene name: relE
• Uniprot ID: Q3K782
• Locus tag: CT157_RS23695
• Protein ID: WP_011335833.1
• Coordinates: 5210968..5211222 (+)
• Length: 85 a.a.

Antitoxin (Protein)

• Gene name: yefM
• Uniprot ID: -
• Locus tag: CT157_RS23690
• Protein ID: WP_085684641.1
• Coordinates: 5210717..5210971 (+)
• Length: 85 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
CT157_RS23665	5206052..5206417	+	366	WP_127799778.1	hypothetical protein	-
CT157_RS23670	5206442..5207188	-	747	WP_127799780.1	hypothetical protein	-
CT157_RS23675	5207308..5207661	+	354	WP_127799782.1	hypothetical protein	-
CT157_RS23680	5207782..5208528	+	747	WP_127799784.1	hypothetical protein	-
CT157_RS23685	5208600..5210519	+	1920	WP_127799786.1	alkaline phosphatase family protein	-
CT157_RS23690	5210717..5210971	+	255	WP_085684641.1	type II toxin-antitoxin system prevent-host-death family antitoxin	Antitoxin
CT157_RS23695	5210968..5211222	+	255	WP_011335833.1	Txe/YoeB family addiction module toxin	Toxin
CT157_RS23700	5211216..5212403	-	1188	WP_127799788.1	aspartate aminotransferase family protein	-
CT157_RS23705	5212506..5213411	+	906	WP_127799790.1	LysR family transcriptional regulator	-
CT157_RS23710	5213457..5213861	+	405	WP_127799792.1	GNAT family N-acetyltransferase	-
CT157_RS23715	5213926..5214450	+	525	WP_127799794.1	hypothetical protein	-
CT157_RS23720	5214624..5215328	+	705	WP_127799796.1	hypothetical protein	-
CT157_RS23725	5215398..5215889	-	492	WP_127799798.1	RidA family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin YoeB (2-84)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-73)

Sequences

Toxin

Protein

• Length: 85 a.a.
• Molecular weight: 9932.56 Da
• Isoelectric Point: 9.6300

>T88145 WP_011335833.1 NZ_CP024646:5210968-5211222 [Pseudomonas syringae]
IKIQFTPTGWEDYLWFQQNDKAGLKRINLLIKAIQRQPFEGLGKPEPLKHNMSGFWSRRITAEHRLVYAIVDGEICVITC
RFHY

Nucleotide

• Length: 255 bp

>T88145 NZ_CP024646:5210968-5211222 [Pseudomonas syringae]
ATAAAAATCCAGTTCACGCCAACGGGCTGGGAAGACTACTTATGGTTTCAGCAAAACGATAAGGCCGGTCTCAAACGAAT
CAATCTTCTGATCAAAGCGATCCAGCGCCAACCCTTTGAAGGCTTGGGTAAACCGGAGCCGCTCAAGCACAACATGAGCG
GCTTCTGGTCACGGCGGATAACTGCCGAGCATCGCCTGGTCTATGCAATCGTAGACGGCGAAATCTGCGTCATAACTTGC
AGATTTCATTACTGA

Antitoxin

Protein

• Length: 85 a.a.
• Molecular weight: 9485.91 Da
• Isoelectric Point: 5.1440

>AT88145 WP_085684641.1 NZ_CP024646:5210717-5210971 [Pseudomonas syringae]
MDTINYTTARAHLAETMERVNEDCAPLLVTRQKGEPVVMMSLAEYNALEETAYLLRSPANAERLIKSIGEMRAGKAKVRQ
LFEE

Nucleotide

• Length: 255 bp

>AT88145 NZ_CP024646:5210717-5210971 [Pseudomonas syringae]
ATGGACACTATCAACTACACCACAGCTCGTGCGCACTTGGCTGAAACCATGGAACGCGTGAATGAAGACTGCGCCCCATT
GTTGGTAACCCGTCAAAAAGGCGAGCCTGTAGTCATGATGTCTCTGGCCGAATACAACGCGCTGGAAGAAACGGCTTATC
TGCTGCGTTCTCCGGCCAATGCCGAGCGCTTGATCAAATCAATTGGCGAAATGCGCGCTGGAAAAGCCAAAGTCAGGCAG
CTGTTCGAAGAATAA

Structures

Toxin

• AlphaFold DB: Q3K782