Detailed information of TA system TA088139

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/ParE-YafN
• Location: 210971..211487
• Replicon: chromosome
• Accession: NZ_CP024646
• Organism: Pseudomonas syringae isolate inb918

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: CT157_RS00885
• Protein ID: WP_127796561.1
• Coordinates: 211206..211487 (+)
• Length: 94 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: A0A0C1VYZ2
• Locus tag: CT157_RS00880
• Protein ID: WP_039773014.1
• Coordinates: 210971..211216 (+)
• Length: 82 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
CT157_RS00845	206242..206847	+	606	WP_127796556.1	adenylyl-sulfate kinase	-
CT157_RS00850	206844..207629	+	786	WP_127796557.1	aspartyl/asparaginyl beta-hydroxylase domain-containing protein	-
CT157_RS00855	207617..208591	+	975	WP_127796558.1	sulfotransferase family protein	-
CT157_RS00860	208557..209315	-	759	WP_007957673.1	slipin family protein	-
CT157_RS00865	209318..209845	-	528	WP_127796559.1	serine protease	-
CT157_RS00870	210042..210503	+	462	WP_127796560.1	YbaK/EbsC family protein	-
CT157_RS00875	210633..210875	+	243	WP_085608554.1	DUF2789 domain-containing protein	-
CT157_RS00880	210971..211216	+	246	WP_039773014.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
CT157_RS00885	211206..211487	+	282	WP_127796561.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
CT157_RS00890	211612..212040	+	429	WP_011331882.1	winged helix DNA-binding protein	-
CT157_RS00895	212037..214100	+	2064	WP_127796562.1	FUSC family protein	-
CT157_RS00900	214097..214306	+	210	WP_007957657.1	DUF1656 domain-containing protein	-
CT157_RS00905	214303..215190	+	888	WP_007957655.1	HlyD family secretion protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (5-83)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (9-67)

Sequences

Toxin

Protein

• Length: 94 a.a.
• Molecular weight: 10969.83 Da
• Isoelectric Point: 10.4588

>T88139 WP_127796561.1 NZ_CP024646:211206-211487 [Pseudomonas syringae]
MTYKLEFLPSAHKEWNKLGHTLRDQFKKKLAERLERPRIPADSLHGMPDCYKIKLKVSGYRLVYQVIEERVVVSVVAVGK
RERGDVYENAKRR

Nucleotide

• Length: 282 bp

>T88139 NZ_CP024646:211206-211487 [Pseudomonas syringae]
ATGACCTATAAGCTCGAATTTCTGCCTTCCGCTCACAAAGAGTGGAACAAACTGGGTCATACGTTGCGTGATCAATTTAA
AAAGAAGCTGGCTGAGCGTCTTGAGCGTCCCCGTATTCCGGCTGACTCCCTCCACGGCATGCCTGATTGCTACAAGATCA
AACTCAAAGTGTCCGGTTATCGACTGGTTTACCAAGTGATCGAAGAGCGAGTGGTTGTCTCGGTAGTCGCCGTGGGTAAG
CGCGAGCGAGGCGACGTCTACGAAAACGCGAAAAGACGCTGA

Antitoxin

Protein

• Length: 82 a.a.
• Molecular weight: 8776.06 Da
• Isoelectric Point: 4.4988

>AT88139 WP_039773014.1 NZ_CP024646:210971-211216 [Pseudomonas syringae]
MQSVLADMAVSVSELKKNPSAVLNGAHGGAVAVLNHNRVMGYMVPADVYEAMMERLDDLELAEIVRSRSHETPIPVSLDD
L

Nucleotide

• Length: 246 bp

>AT88139 NZ_CP024646:210971-211216 [Pseudomonas syringae]
ATGCAAAGTGTTCTGGCCGATATGGCTGTCAGTGTTTCTGAATTGAAGAAAAACCCCTCCGCAGTGCTAAACGGCGCGCA
CGGAGGAGCAGTTGCTGTCCTGAATCACAACCGGGTCATGGGCTACATGGTGCCGGCTGACGTTTACGAAGCCATGATGG
AGCGGCTCGATGATCTCGAGTTGGCAGAAATCGTTCGTTCTCGCAGTCACGAGACTCCCATACCGGTAAGCCTGGATGAC
CTATAA

Structures

Antitoxin

• AlphaFold DB: A0A0C1VYZ2