Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-yefM/YoeB-RelB
Location 1423875..1424391 Replicon chromosome
Accession NZ_CP024627
Organism Vibrio coralliilyticus strain SCSIO 43001

Toxin (Protein)


Gene name relB Uniprot ID -
Locus tag CTT30_RS06855 Protein ID WP_252036458.1
Coordinates 1424122..1424391 (+) Length 90 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag CTT30_RS06850 Protein ID WP_252036457.1
Coordinates 1423875..1424129 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CTT30_RS06815 (CTT30_06855) 1418935..1419348 + 414 WP_252036452.1 hypothetical protein -
CTT30_RS06820 (CTT30_06860) 1419352..1420674 - 1323 WP_252040103.1 IS4 family transposase -
CTT30_RS06825 1421276..1421452 + 177 WP_252036454.1 hypothetical protein -
CTT30_RS06830 (CTT30_06865) 1421563..1422273 + 711 WP_252036455.1 hypothetical protein -
CTT30_RS06835 (CTT30_06870) 1422464..1422877 + 414 WP_038162647.1 RDD family protein -
CTT30_RS06840 (CTT30_06875) 1422896..1422988 + 93 WP_072612521.1 DUF3265 domain-containing protein -
CTT30_RS06845 (CTT30_06880) 1423030..1423656 + 627 WP_252036456.1 LysE family translocator -
CTT30_RS06850 (CTT30_06885) 1423875..1424129 + 255 WP_252036457.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
CTT30_RS06855 (CTT30_06890) 1424122..1424391 + 270 WP_252036458.1 Txe/YoeB family addiction module toxin Toxin
CTT30_RS06860 1424570..1424884 + 315 WP_252036459.1 hypothetical protein -
CTT30_RS06865 1425441..1425593 + 153 WP_252036460.1 hypothetical protein -
CTT30_RS06870 (CTT30_06900) 1425594..1426358 + 765 WP_252036619.1 PhzF family phenazine biosynthesis protein -
CTT30_RS06875 1426376..1426465 + 90 WP_239871702.1 DUF3265 domain-containing protein -
CTT30_RS06880 (CTT30_06910) 1426493..1426762 + 270 WP_252036461.1 hypothetical protein -
CTT30_RS06885 (CTT30_06915) 1426907..1427326 + 420 WP_252036358.1 hypothetical protein -
CTT30_RS06890 (CTT30_06920) 1427450..1427935 + 486 WP_252036462.1 GNAT family N-acetyltransferase -
CTT30_RS06895 (CTT30_06925) 1428107..1428403 - 297 WP_252036463.1 type II toxin-antitoxin system RelE/ParE family toxin -
CTT30_RS06900 (CTT30_06930) 1428410..1428652 - 243 WP_005526987.1 type II toxin-antitoxin system Phd/YefM family antitoxin -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 1303146..1429994 126848
- flank IS/Tn - - 1419352..1420674 1322
- inside Integron - - 1302139..1428858 126719


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(10-89)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 90 a.a.        Molecular weight: 10600.93 Da        Isoelectric Point: 7.9816

>T88108 WP_252036458.1 NZ_CP024627:1424122-1424391 [Vibrio coralliilyticus]
MSSSQRLLSWTDDAWDDYLYWQTQDKKTLKRINKLINDVKRSPFEGIGKPEPLKENLSGFWSRRVDDTNRLVYAVDDQAI
TIISCRYHY

Download         Length: 270 bp

>T88108 NZ_CP024627:1424122-1424391 [Vibrio coralliilyticus]
ATGAGTAGTAGTCAACGTTTACTATCGTGGACTGATGACGCTTGGGATGACTACCTGTATTGGCAAACTCAAGACAAGAA
AACACTCAAGCGCATCAACAAACTCATCAATGATGTAAAGCGCTCCCCATTTGAGGGTATCGGTAAACCAGAGCCGTTAA
AAGAGAACTTATCTGGTTTTTGGTCTCGTCGTGTTGATGACACTAATAGGCTTGTTTACGCAGTCGATGATCAAGCGATA
ACGATAATCTCGTGTCGTTACCACTACTAA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9483.63 Da        Isoelectric Point: 5.0623

>AT88108 WP_252036457.1 NZ_CP024627:1423875-1424129 [Vibrio coralliilyticus]
MRIVSFTEARNGLKAVLDGVVNDADTTVITRRDSEDAVVMSLDYYNSLMETVHLLRSPQNAEHLNRSIAQYRAGKTTTRE
LIDE

Download         Length: 255 bp

>AT88108 NZ_CP024627:1423875-1424129 [Vibrio coralliilyticus]
ATGAGAATCGTATCTTTTACTGAAGCTAGAAATGGTCTTAAAGCTGTTTTGGACGGTGTAGTTAATGACGCTGATACAAC
AGTTATTACACGCCGTGATTCTGAAGATGCTGTGGTTATGTCTTTAGACTACTACAATAGCCTTATGGAGACCGTTCACT
TACTACGCTCTCCTCAAAACGCTGAACACCTAAACCGTTCGATAGCACAGTACCGCGCTGGTAAAACAACAACACGAGAG
TTAATTGATGAGTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References