Detailed information of TA system TA088105

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/RelE(toxin)
• Location: 1353992..1354551
• Replicon: chromosome
• Accession: NZ_CP024627
• Organism: Vibrio coralliilyticus strain SCSIO 43001

Toxin (Protein)

• Gene name: relE
• Uniprot ID: A0A7H5CQX1
• Locus tag: CTT30_RS06295
• Protein ID: WP_025796573.1
• Coordinates: 1353992..1354270 (-)
• Length: 93 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: CTT30_RS06300
• Protein ID: WP_239871581.1
• Coordinates: 1354267..1354551 (-)
• Length: 95 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
CTT30_RS06265 (CTT30_06325)	1349447..1349902	+	456	Protein_1202	GNAT family N-acetyltransferase	-
CTT30_RS06270 (CTT30_06330)	1350574..1351515	+	942	WP_193275176.1	DUF4263 domain-containing protein	-
CTT30_RS06275 (CTT30_06335)	1351540..1351632	+	93	WP_193275177.1	DUF3265 domain-containing protein	-
CTT30_RS06280 (CTT30_06340)	1351690..1352376	+	687	WP_252036381.1	hypothetical protein	-
CTT30_RS06285 (CTT30_06350)	1352646..1353152	-	507	WP_252036382.1	HNH endonuclease signature motif containing protein	-
CTT30_RS06290 (CTT30_06355)	1353582..1353818	+	237	WP_252036383.1	hypothetical protein	-
CTT30_RS06295 (CTT30_06360)	1353992..1354270	-	279	WP_025796573.1	type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family	Toxin
CTT30_RS06300 (CTT30_06365)	1354267..1354551	-	285	WP_239871581.1	type II toxin-antitoxin system RelB/DinJ family antitoxin	Antitoxin
CTT30_RS06305 (CTT30_06370)	1354764..1355081	+	318	WP_252036384.1	hypothetical protein	-
CTT30_RS06310 (CTT30_06375)	1355361..1355582	+	222	WP_004400149.1	VF530 family protein	-
CTT30_RS06315	1356029..1356175	+	147	WP_252036385.1	hypothetical protein	-
CTT30_RS06320 (CTT30_06385)	1356185..1356514	+	330	WP_252036386.1	hypothetical protein	-
CTT30_RS06325 (CTT30_06390)	1356651..1357457	+	807	WP_252036387.1	deaminase	-
CTT30_RS06330	1357947..1358105	+	159	WP_252036388.1	hypothetical protein	-
CTT30_RS06335 (CTT30_06400)	1358112..1358651	+	540	WP_252036389.1	hypothetical protein	-
CTT30_RS06340 (CTT30_06405)	1358787..1359104	+	318	WP_252036390.1	CPCC family cysteine-rich protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Genomic island	-	-	1303146..1429994	126848
	-	inside	Integron	-	-	1302139..1428858	126719

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (2-89)

Antitoxin

• RelB antitoxin/Antitoxin DinJ (5-44)

Sequences

Toxin

Protein

• Length: 93 a.a.
• Molecular weight: 10916.54 Da
• Isoelectric Point: 4.3697

>T88105 WP_025796573.1 NZ_CP024627:c1354270-1353992 [Vibrio coralliilyticus]
MILWEEESLNDREKIFEFLYDFNPEAADKTDDIIEAKVENLLEQPHMGVQRDGIRGRLLIIPEISMIVSYWVEGDIIRVM
RVLHQKQKFPTD

Nucleotide

• Length: 279 bp

>T88105 NZ_CP024627:c1354270-1353992 [Vibrio coralliilyticus]
ATGATTTTGTGGGAAGAAGAGTCTCTCAACGATCGCGAAAAGATCTTTGAGTTTCTCTACGACTTCAACCCCGAAGCTGC
TGACAAAACCGACGATATTATTGAAGCAAAAGTTGAGAACCTTTTAGAGCAACCTCATATGGGAGTCCAGCGTGACGGAA
TTAGAGGGCGATTGCTCATTATTCCTGAGATTTCGATGATTGTTTCCTACTGGGTTGAAGGTGATATCATTCGAGTTATG
CGCGTGCTACACCAAAAACAAAAATTCCCAACGGACTAA

Antitoxin

Protein

• Length: 95 a.a.
• Molecular weight: 10985.32 Da
• Isoelectric Point: 8.0498

>AT88105 WP_239871581.1 NZ_CP024627:c1354551-1354267 [Vibrio coralliilyticus]
MDTRIQFRVDEETKRLAQQMAESQGRTLSDACRELTEQLADQQRKTLSHDAWLTEQINLAFEKFDSGKATFIDHESAKSR
MDERKAKIRNRGKL

Nucleotide

• Length: 285 bp

>AT88105 NZ_CP024627:c1354551-1354267 [Vibrio coralliilyticus]
ATGGACACTAGAATTCAATTTCGTGTTGATGAAGAAACGAAGCGACTAGCCCAACAAATGGCTGAAAGCCAAGGCAGAAC
ACTAAGTGATGCTTGTCGTGAACTGACTGAGCAACTGGCTGACCAACAGAGAAAGACTTTATCTCACGACGCATGGTTAA
CTGAACAAATTAACTTAGCTTTTGAGAAGTTTGACTCAGGAAAAGCCACTTTTATTGACCATGAGTCAGCTAAATCTCGT
ATGGACGAGCGTAAAGCTAAAATCCGTAACCGAGGCAAATTATGA

Structures

Toxin

• AlphaFold DB: A0A7H5CQX1