Detailed information of TA system TA088102

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relB-yefM/YoeB-RelB
• Location: 2729132..2729645
• Replicon: chromosome
• Accession: NZ_CP024621
• Organism: Halomonas meridiana strain SCSIO 43005

Toxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: CTT34_RS13075
• Protein ID: WP_159342812.1
• Coordinates: 2729132..2729398 (-)
• Length: 89 a.a.

Antitoxin (Protein)

• Gene name: yefM
• Uniprot ID: -
• Locus tag: CTT34_RS13080
• Protein ID: WP_159342813.1
• Coordinates: 2729391..2729645 (-)
• Length: 85 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
CTT34_RS13045	2724148..2725764	-	1617	WP_159342808.1	patatin-like phospholipase family protein	-
CTT34_RS13050	2725827..2726426	-	600	WP_159342809.1	TIR domain-containing protein	-
CTT34_RS13055	2726655..2727140	-	486	WP_159342810.1	TIR domain-containing protein	-
CTT34_RS13060	2727151..2727678	-	528	WP_062372669.1	toll/interleukin-1 receptor domain-containing protein	-
CTT34_RS13065	2727846..2728166	-	321	WP_159343796.1	DUF427 domain-containing protein	-
CTT34_RS13070	2728269..2729039	-	771	WP_159342811.1	carbon-nitrogen hydrolase family protein	-
CTT34_RS13075	2729132..2729398	-	267	WP_159342812.1	Txe/YoeB family addiction module toxin	Toxin
CTT34_RS13080	2729391..2729645	-	255	WP_159342813.1	type II toxin-antitoxin system prevent-host-death family antitoxin	Antitoxin
CTT34_RS13085	2729728..2730063	-	336	WP_009100498.1	PhnA domain-containing protein	-
CTT34_RS13090	2730169..2730531	-	363	WP_153842707.1	helix-turn-helix transcriptional regulator	-
CTT34_RS13095	2730624..2730953	+	330	WP_159342814.1	nuclear transport factor 2 family protein	-
CTT34_RS13100	2730950..2731723	+	774	WP_159342815.1	SDR family oxidoreductase	-
CTT34_RS13105	2731809..2732777	+	969	WP_159342816.1	putative zinc-binding metallopeptidase	-
CTT34_RS13110	2732803..2733696	-	894	WP_159342817.1	dihydrodipicolinate synthase family protein	-
CTT34_RS13115	2733743..2734063	-	321	WP_159342818.1	hypothetical protein	-
CTT34_RS13120	2734106..2734390	-	285	WP_159342819.1	type II toxin-antitoxin system RelE/ParE family toxin	-
CTT34_RS13125	2734380..2734631	-	252	WP_062372637.1	type II toxin-antitoxin system Phd/YefM family antitoxin	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Genomic island	-	-	2721550..2729645	8095

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin YoeB (8-88)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-74)

Sequences

Toxin

Protein

• Length: 89 a.a.
• Molecular weight: 10553.00 Da
• Isoelectric Point: 9.0223

>T88102 WP_159342812.1 NZ_CP024621:c2729398-2729132 [Halomonas meridiana]
MSSQRLLCWTDESWNDYVYWQAQDKKTLKRINKLINDVKRSPFEGIGKPEPLKENLAGFWSRRIDDTHRLVYAVDHHAIT
VISCRYHY

Nucleotide

• Length: 267 bp

>T88102 NZ_CP024621:c2729398-2729132 [Halomonas meridiana]
ATGAGTAGTCAGCGACTGTTGTGTTGGACAGATGAATCTTGGAACGACTACGTCTACTGGCAAGCGCAGGATAAGAAAAC
CCTTAAGCGCATTAATAAGCTGATAAACGATGTAAAGCGCTCCCCCTTTGAGGGAATCGGCAAGCCAGAGCCCTTAAAAG
AAAACCTAGCGGGCTTTTGGTCTCGACGTATAGACGATACTCATCGGCTTGTTTATGCAGTCGATCACCACGCGATCACT
GTCATTTCTTGCCGCTATCACTATTAG

Antitoxin

Protein

• Length: 85 a.a.
• Molecular weight: 9398.58 Da
• Isoelectric Point: 5.6558

>AT88102 WP_159342813.1 NZ_CP024621:c2729645-2729391 [Halomonas meridiana]
MKIVSFTEARNGLKAVLDGVVNDADTTVITRRDAEDAVVMSLDYYNSLMETVHLLRSPNNAKHLNRSIAQYRAGQTSARE
LMDE

Nucleotide

• Length: 255 bp

>AT88102 NZ_CP024621:c2729645-2729391 [Halomonas meridiana]
ATGAAAATCGTGTCTTTTACAGAAGCGAGGAATGGCTTGAAAGCTGTGCTGGATGGCGTCGTTAATGATGCGGATACCAC
CGTGATCACGCGCAGGGATGCGGAAGATGCCGTGGTGATGTCGCTGGATTATTACAATAGCCTAATGGAAACAGTGCACC
TGCTTCGTTCGCCTAATAATGCTAAACACCTTAACCGCTCAATAGCGCAATATCGGGCTGGCCAAACAAGCGCACGCGAG
TTAATGGATGAGTAG