Detailed information of TA system TA088096

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): NpoTA/ParE(toxin)
• Location: 1483493..1484608
• Replicon: chromosome
• Accession: NZ_CP024620
• Organism: Acinetobacter indicus strain SGAir0564

Toxin (Protein)

• Gene name: NpoT
• Uniprot ID: -
• Locus tag: CTZ23_RS07135
• Protein ID: WP_045794824.1
• Coordinates: 1483493..1483657 (-)
• Length: 55 a.a.

Antitoxin (Protein)

• Gene name: NpoA
• Uniprot ID: -
• Locus tag: CTZ23_RS07140
• Protein ID: WP_045794748.1
• Coordinates: 1483739..1484608 (-)
• Length: 290 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
CTZ23_RS07120	1479470..1480492	+	1023	WP_104988595.1	iron-sulfur cluster-binding domain-containing protein	-
CTZ23_RS07125	1480516..1481673	+	1158	WP_171249276.1	acyl-CoA desaturase	-
CTZ23_RS07130	1481989..1483392	+	1404	WP_104988596.1	iron-containing redox enzyme family protein	-
CTZ23_RS07135	1483493..1483657	-	165	WP_045794824.1	hypothetical protein	Toxin
CTZ23_RS07140	1483739..1484608	-	870	WP_045794748.1	SDR family oxidoreductase	Antitoxin
CTZ23_RS07145	1484711..1484950	-	240	WP_045794747.1	DUF2171 domain-containing protein	-
CTZ23_RS07150	1485609..1486850	+	1242	WP_045794746.1	MFS transporter	-
CTZ23_RS07155	1487288..1488316	+	1029	WP_104988597.1	KGG domain-containing protein	-
CTZ23_RS07160	1488505..1488954	-	450	WP_045796755.1	cyanase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Integrative and Conjugative Element	-	-	1385710..1814924	429214

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 55 a.a.
• Molecular weight: 6210.81 Da
• Isoelectric Point: 10.1466

>T88096 WP_045794824.1 NZ_CP024620:c1483657-1483493 [Acinetobacter indicus]
MSRGDKSVYTDKQKRQARHIIESEKERGHSEEEAERIGWSTVNKQDGGGKKKSH

Nucleotide

• Length: 165 bp

>T88096 NZ_CP024620:c1483657-1483493 [Acinetobacter indicus]
ATGTCTAGAGGTGATAAGTCGGTCTATACCGACAAGCAGAAACGTCAGGCTCGCCATATTATTGAATCGGAAAAAGAGCG
TGGCCATTCCGAGGAAGAAGCAGAACGTATTGGCTGGTCTACCGTCAATAAACAGGATGGCGGCGGTAAAAAGAAATCCC
ACTAA

Antitoxin

Protein

• Length: 290 a.a.
• Molecular weight: 31852.95 Da
• Isoelectric Point: 4.7467

>AT88096 WP_045794748.1 NZ_CP024620:c1484608-1483739 [Acinetobacter indicus]
MNHYPDSPSPQEKQEHQPGVQYKMTPEPEIIKSNYQGSQKLKDKVALITGGDSGIGRSVAVLFAREGANIIIPYLEEDQD
AQDTKRLVEQEGCQCLLIQCDLRQHAAVQQMVDLALQQFPHINILVNNAAVQYPQKTIEDINPEQLHKTFETNLYPLFYV
TQLLIPQMQPGDSIINTTSITSYQGHNELIDYASTKGAITAFTRSLSTNLLKNKTGIRVNGVAPGPIWTPLIPSSFDEEQ
LKGFGEDTPMGRMGQPSEVAPAYLFLASDEASYISGQVIHVNGGTIVNG

Nucleotide

• Length: 870 bp

>AT88096 NZ_CP024620:c1484608-1483739 [Acinetobacter indicus]
ATGAATCATTATCCTGACAGCCCATCTCCGCAAGAGAAACAGGAGCATCAGCCTGGTGTACAATATAAAATGACGCCCGA
ACCTGAAATTATTAAAAGCAATTATCAGGGCAGTCAAAAACTCAAAGACAAGGTAGCCTTAATTACCGGCGGTGACAGCG
GCATCGGCCGATCTGTGGCGGTGCTGTTTGCCCGCGAAGGTGCCAATATTATTATTCCCTATTTAGAAGAAGATCAGGAT
GCGCAAGACACCAAGCGTCTGGTCGAGCAGGAAGGCTGTCAATGTCTGCTGATTCAATGTGACCTGCGCCAACATGCGGC
GGTACAGCAGATGGTCGATTTGGCCTTACAGCAGTTTCCGCATATTAATATTCTGGTCAATAATGCCGCCGTACAATATC
CACAAAAAACCATTGAAGATATTAATCCCGAACAGCTGCATAAAACCTTTGAAACCAACCTCTACCCGCTGTTTTATGTG
ACCCAGCTGCTGATTCCTCAAATGCAGCCCGGTGACAGTATTATCAATACCACCAGTATCACCAGTTATCAGGGCCATAA
TGAGCTGATTGATTATGCCAGTACCAAAGGGGCAATTACTGCCTTTACCCGTAGCCTGTCGACCAACTTGCTAAAAAATA
AAACCGGGATTCGGGTGAATGGTGTCGCACCCGGCCCAATCTGGACGCCGTTAATTCCGAGTAGTTTTGATGAAGAACAG
CTAAAAGGTTTTGGTGAAGATACCCCCATGGGCCGTATGGGTCAGCCAAGTGAAGTTGCGCCAGCTTATCTGTTTTTAGC
CTCCGATGAAGCCAGCTATATTTCCGGTCAGGTGATTCATGTCAATGGCGGTACCATTGTCAATGGTTAA