Detailed information of TA system TA088095

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): cptAB/-
• Location: 415675..416311
• Replicon: chromosome
• Accession: NZ_CP024620
• Organism: Acinetobacter indicus strain SGAir0564

Toxin (Protein)

• Gene name: cptA
• Uniprot ID: -
• Locus tag: CTZ23_RS02085
• Protein ID: WP_104988132.1
• Coordinates: 415919..416311 (+)
• Length: 131 a.a.

Antitoxin (Protein)

• Gene name: cptB
• Uniprot ID: N9KY84
• Locus tag: CTZ23_RS02080
• Protein ID: WP_005180238.1
• Coordinates: 415675..415932 (+)
• Length: 86 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
CTZ23_RS02060	411150..412157	+	1008	WP_104988129.1	DNA-directed RNA polymerase subunit alpha	-
CTZ23_RS02065	412177..412542	+	366	WP_004754212.1	50S ribosomal protein L17	-
CTZ23_RS02070	412741..414231	+	1491	WP_104988130.1	NAD(P)/FAD-dependent oxidoreductase	-
CTZ23_RS02075	414319..415491	-	1173	WP_104988131.1	acyl-CoA dehydrogenase family protein	-
CTZ23_RS02080	415675..415932	+	258	WP_005180238.1	succinate dehydrogenase assembly factor 2	Antitoxin
CTZ23_RS02085	415919..416311	+	393	WP_104988132.1	hypothetical protein	Toxin
CTZ23_RS02090	416828..417901	+	1074	WP_104988133.1	hypothetical protein	-
CTZ23_RS02095	417957..418529	+	573	WP_104988134.1	rhombosortase	-
CTZ23_RS02100	418710..420986	+	2277	WP_104988135.1	TRAP transporter large permease subunit	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

• Flavinator of succinate dehydrogenase (10-82)

Sequences

Toxin

Protein

• Length: 131 a.a.
• Molecular weight: 14960.81 Da
• Isoelectric Point: 10.4540

>T88095 WP_104988132.1 NZ_CP024620:415919-416311 [Acinetobacter indicus]
MSMAKRDFQLKPSRLALLFQLSLLILFSVLSFQLLHPLLWLLGLLLAAVSYYGFQRRSQLTALAHLDGAEWSLQFNSGPK
IQRGLLDHILDHQLYLVLYFHHAPVKSAVIWRDQVPLAEWKALKTLVKTI

Nucleotide

• Length: 393 bp

>T88095 NZ_CP024620:415919-416311 [Acinetobacter indicus]
ATGTCCATGGCTAAGCGCGACTTTCAGCTGAAACCGAGCCGTCTGGCACTGCTGTTTCAGCTGAGCCTGCTGATTCTATT
TTCTGTTTTAAGTTTTCAATTATTGCATCCGCTGCTTTGGCTGCTGGGTCTGCTGCTGGCGGCTGTTAGTTATTACGGGT
TTCAGCGACGCTCTCAATTGACCGCCTTGGCACATTTAGATGGGGCAGAGTGGAGTCTGCAGTTTAATTCTGGCCCCAAG
ATTCAACGCGGTCTGCTCGATCATATTCTGGATCATCAGCTGTATCTGGTGCTGTATTTTCATCATGCACCAGTCAAATC
TGCAGTCATCTGGCGTGATCAGGTTCCACTTGCAGAGTGGAAAGCCTTAAAAACATTGGTAAAAACCATCTAA

Antitoxin

Protein

• Length: 86 a.a.
• Molecular weight: 10220.62 Da
• Isoelectric Point: 4.6150

>AT88095 WP_005180238.1 NZ_CP024620:415675-415932 [Acinetobacter indicus]
MSEDISLEERKVIYRARRGLKEIDVYFDPYVKNYYLTADPEEKATFAALVEQEDPDLLDWFMEVSEPPRPEMRELIRKLK
HYVHG

Nucleotide

• Length: 258 bp

>AT88095 NZ_CP024620:415675-415932 [Acinetobacter indicus]
ATGAGTGAAGACATTAGCTTAGAAGAGCGTAAAGTGATTTATCGTGCCCGTCGCGGTTTAAAGGAAATTGATGTCTACTT
TGATCCTTATGTAAAAAACTATTATTTAACCGCTGATCCAGAAGAAAAAGCCACATTTGCTGCGCTGGTTGAACAGGAAG
ATCCAGATTTGCTGGACTGGTTTATGGAAGTGTCTGAACCGCCACGCCCGGAAATGCGCGAGCTGATCCGTAAATTAAAA
CACTATGTCCATGGCTAA

Structures

Antitoxin

• AlphaFold DB: N9KY84