Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ParE-CopA/ParE-RHH
Location 5819039..5819663 Replicon chromosome
Accession NZ_CP024608
Organism Massilia violaceinigra strain B2

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag CR152_RS24970 Protein ID WP_099879479.1
Coordinates 5819039..5819329 (-) Length 97 a.a.

Antitoxin (Protein)


Gene name copA Uniprot ID -
Locus tag CR152_RS24975 Protein ID WP_099882753.1
Coordinates 5819379..5819663 (-) Length 95 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CR152_RS24945 5815008..5815892 - 885 WP_099882751.1 PhzF family phenazine biosynthesis protein -
CR152_RS24950 5815900..5816352 - 453 WP_099879471.1 CBS domain-containing protein -
CR152_RS24955 5816574..5817884 + 1311 WP_099879473.1 O-acetylhomoserine aminocarboxypropyltransferase -
CR152_RS24960 5817886..5818695 + 810 WP_099879475.1 alpha/beta hydrolase -
CR152_RS24965 5818714..5819019 + 306 WP_099879477.1 DUF962 domain-containing protein -
CR152_RS24970 5819039..5819329 - 291 WP_099879479.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
CR152_RS24975 5819379..5819663 - 285 WP_099882753.1 CopG family ribbon-helix-helix protein Antitoxin
CR152_RS24980 5819821..5821176 - 1356 WP_099879481.1 YihY family inner membrane protein -
CR152_RS24985 5821296..5821907 + 612 WP_099879483.1 NAD(P)H:quinone oxidoreductase -
CR152_RS24990 5821907..5822311 + 405 WP_099879486.1 DUF2069 domain-containing protein -
CR152_RS24995 5822404..5823741 + 1338 WP_099882755.1 FAD-binding oxidoreductase -
CR152_RS25000 5823759..5824211 + 453 WP_099879488.1 DUF4124 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-93)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 11161.91 Da        Isoelectric Point: 11.4747

>T88051 WP_099879479.1 NZ_CP024608:c5819329-5819039 [Massilia violaceinigra]
MPQVRFSKRALLDLKRLREFLRPKNQAAARRATVAIIRSIQVLSQHPGIGRPIQNMSDGYYELLISFGNTGYIARYRHNK
DEVTILSVRHQKETQQ

Download         Length: 291 bp

>T88051 NZ_CP024608:c5819329-5819039 [Massilia violaceinigra]
ATGCCACAAGTACGCTTTTCAAAACGGGCGCTACTTGACCTGAAAAGGTTGCGGGAATTTTTGCGGCCGAAAAATCAAGC
GGCAGCCAGGCGCGCCACCGTAGCGATAATCAGGTCCATCCAAGTGCTGAGCCAGCATCCGGGAATCGGACGTCCGATAC
AGAACATGTCGGACGGTTACTACGAGTTGCTTATTTCCTTCGGCAATACCGGCTACATCGCTCGCTATCGTCACAATAAA
GATGAGGTCACAATTTTGTCGGTGAGGCATCAAAAGGAAACTCAGCAATAG

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 11027.32 Da        Isoelectric Point: 4.3672

>AT88051 WP_099882753.1 NZ_CP024608:c5819663-5819379 [Massilia violaceinigra]
MSDLTSLALELDQETHLRLERLAESRRQTPLLIMHEAIVQYLEREEKREASRQETLDAWKEYQVTGLHVTGDEVIAWLET
WGDENELPAPECHK

Download         Length: 285 bp

>AT88051 NZ_CP024608:c5819663-5819379 [Massilia violaceinigra]
ATGTCCGACCTAACATCGCTGGCGCTTGAACTTGATCAGGAAACGCACCTCCGTCTGGAACGCTTGGCCGAATCGCGCCG
GCAGACACCGCTTCTGATAATGCACGAAGCAATTGTTCAATATCTTGAGCGTGAAGAAAAGCGCGAAGCTTCCCGTCAAG
AAACCCTCGACGCATGGAAGGAATATCAGGTGACCGGGTTGCACGTGACAGGTGACGAGGTAATAGCATGGCTTGAAACA
TGGGGCGACGAAAACGAGCTCCCCGCGCCGGAGTGCCACAAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References