Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 3884494..3885044 Replicon chromosome
Accession NZ_CP024608
Organism Massilia violaceinigra strain B2

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag CR152_RS17335 Protein ID WP_099876406.1
Coordinates 3884494..3884769 (-) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag CR152_RS17340 Protein ID WP_099876407.1
Coordinates 3884769..3885044 (-) Length 92 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CR152_RS17315 3880063..3880662 + 600 WP_099876401.1 MarC family protein -
CR152_RS17320 3880786..3882873 - 2088 WP_099876403.1 excinuclease ABC subunit UvrB -
CR152_RS17325 3882981..3884195 + 1215 WP_099876404.1 aspartate/tyrosine/aromatic aminotransferase -
CR152_RS17335 3884494..3884769 - 276 WP_099876406.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
CR152_RS17340 3884769..3885044 - 276 WP_099876407.1 ribbon-helix-helix domain-containing protein Antitoxin
CR152_RS17345 3885386..3886201 - 816 WP_099876409.1 hypothetical protein -
CR152_RS17350 3886191..3886502 - 312 WP_099876410.1 hypothetical protein -
CR152_RS17360 3887067..3887675 + 609 WP_099876412.1 hypothetical protein -
CR152_RS17370 3887930..3888868 + 939 WP_157778563.1 hypothetical protein -
CR152_RS17375 3888938..3889786 + 849 WP_157778564.1 endonuclease/exonuclease/phosphatase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-90)

Antitoxin

Ribbon-helix-helix protein, CopG

(9-46)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10488.31 Da        Isoelectric Point: 10.5207

>T88050 WP_099876406.1 NZ_CP024608:c3884769-3884494 [Massilia violaceinigra]
MQPQWTSKALADLVRLHEFLAAVNKPAAARMLKSLMAAPASLVANPRMGEKLDEFEPREVRRILVGHYEMRYEIAGSAVY
ILRVWHTREKR

Download         Length: 276 bp

>T88050 NZ_CP024608:c3884769-3884494 [Massilia violaceinigra]
ATGCAGCCGCAATGGACCAGCAAGGCGCTTGCTGACCTGGTCCGCCTGCATGAATTCCTTGCGGCCGTGAATAAGCCCGC
AGCGGCGCGCATGTTGAAGTCGCTCATGGCAGCCCCGGCAAGTTTGGTGGCAAATCCACGCATGGGCGAAAAACTCGACG
AATTTGAACCGCGCGAGGTCAGAAGAATTCTGGTGGGCCACTATGAGATGCGCTATGAAATAGCCGGATCCGCGGTCTAT
ATTCTGCGCGTGTGGCATACGCGCGAGAAACGCTAA

Antitoxin


Download         Length: 92 a.a.        Molecular weight: 10067.39 Da        Isoelectric Point: 4.6135

>AT88050 WP_099876407.1 NZ_CP024608:c3885044-3884769 [Massilia violaceinigra]
MAPAETKVLTAHVPLSLADKVDELAARLERSQGWVIKQALSAWVDQEEERSRLTREALADVDAGRVIDHQTIQRWADSLA
TDNPLPAPMVP

Download         Length: 276 bp

>AT88050 NZ_CP024608:c3885044-3884769 [Massilia violaceinigra]
ATGGCTCCTGCTGAAACCAAAGTGCTCACCGCGCACGTTCCGTTATCGTTGGCAGACAAGGTTGACGAGCTGGCCGCCCG
GCTTGAGCGTTCGCAGGGATGGGTTATCAAACAGGCCCTGAGCGCATGGGTCGATCAGGAAGAAGAGCGCAGCCGCCTCA
CGCGTGAAGCCTTGGCCGACGTCGATGCGGGACGCGTCATCGATCACCAAACGATCCAGCGCTGGGCTGATAGCCTCGCC
ACGGACAACCCGCTTCCGGCACCCATGGTGCCCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References