Detailed information of TA system TA088039

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): cptAB/-
• Location: 500768..501421
• Replicon: chromosome
• Accession: NZ_CP024576
• Organism: Acinetobacter baumannii strain AbPK1

Toxin (Protein)

• Gene name: cptA
• Uniprot ID: -
• Locus tag: CTI08_RS02405
• Protein ID: WP_000607077.1
• Coordinates: 501032..501421 (+)
• Length: 130 a.a.

Antitoxin (Protein)

• Gene name: cptB
• Uniprot ID: V5V966
• Locus tag: CTI08_RS02400
• Protein ID: WP_001288210.1
• Coordinates: 500768..501025 (+)
• Length: 86 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
CTI08_RS02380	496284..497291	+	1008	WP_000198631.1	DNA-directed RNA polymerase subunit alpha	-
CTI08_RS02385	497310..497687	+	378	WP_001216380.1	50S ribosomal protein L17	-
CTI08_RS02390	497869..499359	+	1491	WP_000415125.1	NAD(P)/FAD-dependent oxidoreductase	-
CTI08_RS02395	499408..500580	-	1173	WP_001190542.1	acyl-CoA dehydrogenase family protein	-
CTI08_RS02400	500768..501025	+	258	WP_001288210.1	succinate dehydrogenase assembly factor 2	Antitoxin
CTI08_RS02405	501032..501421	+	390	WP_000607077.1	membrane protein	Toxin
CTI08_RS02410	502191..503276	+	1086	WP_000049106.1	hypothetical protein	-
CTI08_RS02415	503354..503920	+	567	WP_000651538.1	rhombosortase	-
CTI08_RS02420	504108..506303	+	2196	WP_001158906.1	TRAP transporter large permease subunit	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

• Flavinator of succinate dehydrogenase (10-82)

Sequences

Toxin

Protein

• Length: 130 a.a.
• Molecular weight: 15552.88 Da
• Isoelectric Point: 10.4313

>T88039 WP_000607077.1 NZ_CP024576:501032-501421 [Acinetobacter baumannii]
MINHLNFKLKYSRFSIIFQFFIGLSLAVLFYQLMPLLWWLVVISLLFISFIFFLKRPQLAQIAYLDKKLWSLAYKSQNTV
SRVKILKIIDCQIFIVIYFEGHKTLTSIIWFDQMSLAEWKKLKTLEKLY

Nucleotide

• Length: 390 bp

>T88039 NZ_CP024576:501032-501421 [Acinetobacter baumannii]
TTGATCAACCATTTGAATTTTAAGCTGAAATATAGTCGTTTTTCGATTATATTTCAGTTTTTTATTGGCTTAAGCTTAGC
AGTTCTATTTTATCAATTAATGCCGTTACTATGGTGGTTAGTTGTAATCAGCTTACTATTTATCAGCTTTATTTTCTTTT
TAAAGCGTCCGCAGCTTGCACAAATTGCTTATTTAGATAAAAAACTATGGTCGCTTGCTTATAAGTCACAGAACACCGTT
TCTCGCGTCAAAATTTTAAAAATAATTGATTGTCAGATTTTCATAGTGATCTATTTTGAAGGTCATAAAACACTAACTTC
TATCATTTGGTTTGATCAAATGTCATTAGCAGAGTGGAAAAAGCTTAAAACTTTAGAAAAACTCTATTAA

Antitoxin

Protein

• Length: 86 a.a.
• Molecular weight: 10318.77 Da
• Isoelectric Point: 4.6150

>AT88039 WP_001288210.1 NZ_CP024576:500768-501025 [Acinetobacter baumannii]
MSEEMTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIYKLK
HYVHG

Nucleotide

• Length: 258 bp

>AT88039 NZ_CP024576:500768-501025 [Acinetobacter baumannii]
ATGTCTGAAGAAATGACCTTGGAAGAACGTAAAGTAATCTATCGCGCACGTCGTGGTTTAAAGGAAATTGATGTCTATTT
TGACCCTTATGTGAAAAATTATTATTTAAAGGCAGACCCGGCAGAAAAAGCGTTGTTTGCTGAGTTGGTAGAACAGGAAG
ACCCTGATTTACTAGATTGGTTTATGGAAGTATCAGAACCACCACGTACCGAATTACGTGACTTTATCTATAAATTAAAA
CACTATGTTCATGGTTAA

Structures

Antitoxin

• AlphaFold DB: A0A7U4BQM7