Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2787856..2788001 Replicon chromosome
Accession NZ_CP024570
Organism Klebsiella pneumoniae strain INF274

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2787863..2787965 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2787856..2788001 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CTI69_RS14215 2783388..2784821 + 1434 WP_032411854.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
CTI69_RS14220 2784937..2785176 + 240 WP_002911393.1 YebV family protein -
CTI69_RS14225 2785274..2785465 + 192 WP_002911395.1 YebW family protein -
CTI69_RS14230 2785462..2786115 - 654 WP_004180432.1 protein-serine/threonine phosphatase -
CTI69_RS14235 2786272..2787240 + 969 WP_004151446.1 VirK/YbjX family protein -
CTI69_RS29665 2787345..2787488 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 2787856..2788001 + 146 - - Antitoxin
- 2787863..2787965 - 103 - - Toxin
CTI69_RS14245 2788124..2788462 - 339 WP_016529031.1 YebY family protein -
CTI69_RS14250 2788479..2789348 - 870 WP_004189267.1 copper homeostasis membrane protein CopD -
CTI69_RS14255 2789352..2789726 - 375 WP_004151448.1 CopC domain-containing protein YobA -
CTI69_RS14260 2789839..2790069 + 231 WP_002911406.1 DNA polymerase III subunit theta -
CTI69_RS14265 2790148..2790807 + 660 WP_032425085.1 exodeoxyribonuclease X -
CTI69_RS14270 2790811..2792871 - 2061 WP_004151449.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T88023 NZ_CP024570:c2787965-2787863 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT88023 NZ_CP024570:2787856-2788001 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References