Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1933201..1933346 Replicon chromosome
Accession NZ_CP024556
Organism Klebsiella pneumoniae strain INF164

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1933237..1933339 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1933201..1933346 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CTI75_RS09620 1928331..1930391 + 2061 WP_004151449.1 oligopeptidase B -
CTI75_RS09625 1930395..1931054 - 660 WP_032425085.1 exodeoxyribonuclease X -
CTI75_RS09630 1931133..1931363 - 231 WP_002911406.1 DNA polymerase III subunit theta -
CTI75_RS09635 1931476..1931850 + 375 WP_004151448.1 CopC domain-containing protein YobA -
CTI75_RS09640 1931854..1932723 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
CTI75_RS09645 1932740..1933078 + 339 WP_016529031.1 YebY family protein -
- 1933201..1933346 - 146 - - Antitoxin
- 1933237..1933339 + 103 - - Toxin
CTI75_RS30255 1933714..1933857 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
CTI75_RS09655 1933962..1934930 - 969 WP_004151446.1 VirK/YbjX family protein -
CTI75_RS09660 1935087..1935740 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
CTI75_RS09665 1935737..1935928 - 192 WP_002911395.1 YebW family protein -
CTI75_RS09670 1936026..1936265 - 240 WP_002911393.1 YebV family protein -
CTI75_RS09675 1936381..1937814 - 1434 WP_032411854.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T87980 NZ_CP024556:1933237-1933339 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT87980 NZ_CP024556:c1933346-1933201 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References