Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1932972..1933117 Replicon chromosome
Accession NZ_CP024549
Organism Klebsiella pneumoniae strain INF163

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1933008..1933110 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1932972..1933117 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CTI74_RS09600 1928102..1930162 + 2061 WP_004151449.1 oligopeptidase B -
CTI74_RS09605 1930166..1930825 - 660 WP_032425085.1 exodeoxyribonuclease X -
CTI74_RS09610 1930904..1931134 - 231 WP_002911406.1 DNA polymerase III subunit theta -
CTI74_RS09615 1931247..1931621 + 375 WP_004151448.1 CopC domain-containing protein YobA -
CTI74_RS09620 1931625..1932494 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
CTI74_RS09625 1932511..1932849 + 339 WP_016529031.1 YebY family protein -
- 1932972..1933117 - 146 - - Antitoxin
- 1933008..1933110 + 103 - - Toxin
CTI74_RS29680 1933485..1933628 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
CTI74_RS09635 1933733..1934701 - 969 WP_004151446.1 VirK/YbjX family protein -
CTI74_RS09640 1934858..1935511 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
CTI74_RS09645 1935508..1935699 - 192 WP_002911395.1 YebW family protein -
CTI74_RS09650 1935797..1936036 - 240 WP_002911393.1 YebV family protein -
CTI74_RS09655 1936152..1937585 - 1434 WP_032411854.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T87959 NZ_CP024549:1933008-1933110 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT87959 NZ_CP024549:c1933117-1932972 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References