Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1926616..1926761 Replicon chromosome
Accession NZ_CP024548
Organism Klebsiella pneumoniae strain KSB1_7J

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1926652..1926754 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1926616..1926761 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CTI66_RS09695 1921746..1923806 + 2061 WP_004151449.1 oligopeptidase B -
CTI66_RS09700 1923810..1924469 - 660 WP_002911407.1 exodeoxyribonuclease X -
CTI66_RS09705 1924548..1924778 - 231 WP_002911406.1 DNA polymerase III subunit theta -
CTI66_RS09710 1924891..1925265 + 375 WP_004151448.1 CopC domain-containing protein YobA -
CTI66_RS09715 1925269..1926138 + 870 WP_020956678.1 copper homeostasis membrane protein CopD -
CTI66_RS09720 1926155..1926493 + 339 WP_002911404.1 YebY family protein -
- 1926616..1926761 - 146 - - Antitoxin
- 1926652..1926754 + 103 - - Toxin
CTI66_RS27020 1927129..1927272 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
CTI66_RS09730 1927377..1928345 - 969 WP_004151446.1 VirK/YbjX family protein -
CTI66_RS09735 1928502..1929155 + 654 WP_020802220.1 protein-serine/threonine phosphatase -
CTI66_RS09740 1929152..1929343 - 192 WP_002911395.1 YebW family protein -
CTI66_RS09745 1929441..1929680 - 240 WP_002911393.1 YebV family protein -
CTI66_RS09750 1929796..1931229 - 1434 WP_099755895.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T87940 NZ_CP024548:1926652-1926754 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT87940 NZ_CP024548:c1926761-1926616 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References