Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1932206..1932351 Replicon chromosome
Accession NZ_CP024528
Organism Klebsiella pneumoniae strain INF157

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1932242..1932344 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1932206..1932351 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CTI61_RS09620 1927336..1929396 + 2061 WP_004151449.1 oligopeptidase B -
CTI61_RS09625 1929400..1930059 - 660 WP_032425085.1 exodeoxyribonuclease X -
CTI61_RS09630 1930138..1930368 - 231 WP_002911406.1 DNA polymerase III subunit theta -
CTI61_RS09635 1930481..1930855 + 375 WP_004151448.1 CopC domain-containing protein YobA -
CTI61_RS09640 1930859..1931728 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
CTI61_RS09645 1931745..1932083 + 339 WP_016529031.1 YebY family protein -
- 1932206..1932351 - 146 - - Antitoxin
- 1932242..1932344 + 103 - - Toxin
CTI61_RS29885 1932719..1932862 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
CTI61_RS09655 1932967..1933935 - 969 WP_004151446.1 VirK/YbjX family protein -
CTI61_RS09660 1934092..1934745 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
CTI61_RS09665 1934742..1934933 - 192 WP_002911395.1 YebW family protein -
CTI61_RS09670 1935031..1935270 - 240 WP_002911393.1 YebV family protein -
CTI61_RS09675 1935386..1936819 - 1434 WP_032411854.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T87854 NZ_CP024528:1932242-1932344 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT87854 NZ_CP024528:c1932351-1932206 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References