Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 604402..604547 Replicon chromosome
Accession NZ_CP024521
Organism Klebsiella pneumoniae strain INF158

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 604438..604540 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 604402..604547 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CTI59_RS02850 599532..601592 + 2061 WP_004151449.1 oligopeptidase B -
CTI59_RS02855 601596..602255 - 660 WP_032425085.1 exodeoxyribonuclease X -
CTI59_RS02860 602334..602564 - 231 WP_002911406.1 DNA polymerase III subunit theta -
CTI59_RS02865 602677..603051 + 375 WP_004151448.1 CopC domain-containing protein YobA -
CTI59_RS02870 603055..603924 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
CTI59_RS02875 603941..604279 + 339 WP_016529031.1 YebY family protein -
- 604402..604547 - 146 - - Antitoxin
- 604438..604540 + 103 - - Toxin
CTI59_RS29850 604915..605058 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
CTI59_RS02885 605163..606131 - 969 WP_004151446.1 VirK/YbjX family protein -
CTI59_RS02890 606288..606941 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
CTI59_RS02895 606938..607129 - 192 WP_002911395.1 YebW family protein -
CTI59_RS02900 607227..607466 - 240 WP_002911393.1 YebV family protein -
CTI59_RS02905 607582..609015 - 1434 WP_032411854.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T87829 NZ_CP024521:604438-604540 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT87829 NZ_CP024521:c604547-604402 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References