Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | IV | Classification (family/domain) | cptAB/Cpta(toxin) |
Location | 782757..783414 | Replicon | chromosome |
Accession | NZ_CP024496 | ||
Organism | Klebsiella pneumoniae strain KSB1_7E |
Toxin (Protein)
Gene name | cptA | Uniprot ID | W8UCT0 |
Locus tag | CTI55_RS04015 | Protein ID | WP_002916310.1 |
Coordinates | 783004..783414 (+) | Length | 137 a.a. |
Antitoxin (Protein)
Gene name | cptB | Uniprot ID | W8UQ37 |
Locus tag | CTI55_RS04010 | Protein ID | WP_002916312.1 |
Coordinates | 782757..783023 (+) | Length | 89 a.a. |
Genomic Context
Location: 780295..780606 (312 bp)
Type: Others
Protein ID: WP_004144734.1
Type: Others
Protein ID: WP_004144734.1
Location: 780770..781429 (660 bp)
Type: Others
Protein ID: WP_002916317.1
Type: Others
Protein ID: WP_002916317.1
Location: 782757..783023 (267 bp)
Type: Antitoxin
Protein ID: WP_002916312.1
Type: Antitoxin
Protein ID: WP_002916312.1
Location: 783004..783414 (411 bp)
Type: Toxin
Protein ID: WP_002916310.1
Type: Toxin
Protein ID: WP_002916310.1
Location: 784043..784939 (897 bp)
Type: Others
Protein ID: WP_004144729.1
Type: Others
Protein ID: WP_004144729.1
Location: 784962..785675 (714 bp)
Type: Others
Protein ID: WP_002916301.1
Type: Others
Protein ID: WP_002916301.1
Location: 785681..787414 (1734 bp)
Type: Others
Protein ID: WP_004149758.1
Type: Others
Protein ID: WP_004149758.1
Location: 777965..779398 (1434 bp)
Type: Others
Protein ID: WP_004185559.1
Type: Others
Protein ID: WP_004185559.1
Location: 779517..780245 (729 bp)
Type: Others
Protein ID: WP_002916321.1
Type: Others
Protein ID: WP_002916321.1
Location: 781528..782511 (984 bp)
Type: Others
Protein ID: WP_002916313.1
Type: Others
Protein ID: WP_002916313.1
Location: 783421..783942 (522 bp)
Type: Others
Protein ID: WP_004144730.1
Type: Others
Protein ID: WP_004144730.1
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Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
CTI55_RS03985 | 777965..779398 | - | 1434 | WP_004185559.1 | 6-phospho-beta-glucosidase BglA | - |
CTI55_RS03990 | 779517..780245 | - | 729 | WP_002916321.1 | MurR/RpiR family transcriptional regulator | - |
CTI55_RS03995 | 780295..780606 | + | 312 | WP_004144734.1 | N(4)-acetylcytidine aminohydrolase | - |
CTI55_RS04000 | 780770..781429 | + | 660 | WP_002916317.1 | hemolysin III family protein | - |
CTI55_RS04005 | 781528..782511 | - | 984 | WP_002916313.1 | tRNA-modifying protein YgfZ | - |
CTI55_RS04010 | 782757..783023 | + | 267 | WP_002916312.1 | FAD assembly factor SdhE | Antitoxin |
CTI55_RS04015 | 783004..783414 | + | 411 | WP_002916310.1 | protein YgfX | Toxin |
CTI55_RS04020 | 783421..783942 | - | 522 | WP_004144730.1 | flavodoxin FldB | - |
CTI55_RS04025 | 784043..784939 | + | 897 | WP_004144729.1 | site-specific tyrosine recombinase XerD | - |
CTI55_RS04030 | 784962..785675 | + | 714 | WP_002916301.1 | bifunctional protein-disulfide isomerase/oxidoreductase DsbC | - |
CTI55_RS04035 | 785681..787414 | + | 1734 | WP_004149758.1 | single-stranded-DNA-specific exonuclease RecJ | - |
Associated MGEs
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MGE detail | Similar MGEs | Relative position | MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
No matching records found |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 137 a.a. Molecular weight: 16049.85 Da Isoelectric Point: 11.4778
>T87812 WP_002916310.1 NZ_CP024496:783004-783414 [Klebsiella pneumoniae]
VVLWQSDLRISWRAQWFSLLLHGVVAALVLLVPWPLSYTPIWLLLLSLVVFDCVRSQRRIHARRGEIKLLTDSRLRWQNA
EWEILGTPWVINSGMLLRLRHVDTRRGQHLWLAADSMDAGEWRDLRRLVLQKPAQE
VVLWQSDLRISWRAQWFSLLLHGVVAALVLLVPWPLSYTPIWLLLLSLVVFDCVRSQRRIHARRGEIKLLTDSRLRWQNA
EWEILGTPWVINSGMLLRLRHVDTRRGQHLWLAADSMDAGEWRDLRRLVLQKPAQE
Download Length: 411 bp
>T87812 NZ_CP024496:783004-783414 [Klebsiella pneumoniae]
GTGGTCCTGTGGCAATCTGATCTCCGTATCTCCTGGCGCGCGCAGTGGTTTTCCCTGCTGCTTCACGGCGTGGTGGCGGC
CCTGGTGCTGTTGGTTCCCTGGCCGCTGAGCTATACCCCGATCTGGCTGCTGCTGCTGTCGCTGGTGGTCTTCGACTGCG
TGCGCAGCCAGCGGCGGATCCATGCCCGTCGCGGGGAGATAAAACTGCTCACCGATTCCCGTCTTCGCTGGCAAAACGCC
GAATGGGAAATCCTCGGGACGCCGTGGGTTATCAATAGCGGTATGCTGCTGCGTTTGCGCCATGTCGATACCCGGCGCGG
ACAGCATCTTTGGCTGGCGGCGGACAGCATGGACGCCGGAGAGTGGCGCGATCTGCGCCGGCTGGTGCTGCAAAAACCGG
CGCAGGAGTAA
GTGGTCCTGTGGCAATCTGATCTCCGTATCTCCTGGCGCGCGCAGTGGTTTTCCCTGCTGCTTCACGGCGTGGTGGCGGC
CCTGGTGCTGTTGGTTCCCTGGCCGCTGAGCTATACCCCGATCTGGCTGCTGCTGCTGTCGCTGGTGGTCTTCGACTGCG
TGCGCAGCCAGCGGCGGATCCATGCCCGTCGCGGGGAGATAAAACTGCTCACCGATTCCCGTCTTCGCTGGCAAAACGCC
GAATGGGAAATCCTCGGGACGCCGTGGGTTATCAATAGCGGTATGCTGCTGCGTTTGCGCCATGTCGATACCCGGCGCGG
ACAGCATCTTTGGCTGGCGGCGGACAGCATGGACGCCGGAGAGTGGCGCGATCTGCGCCGGCTGGTGCTGCAAAAACCGG
CGCAGGAGTAA
Antitoxin
Download Length: 89 a.a. Molecular weight: 10480.98 Da Isoelectric Point: 5.1116
>AT87812 WP_002916312.1 NZ_CP024496:782757-783023 [Klebsiella pneumoniae]
MDINNKARIHWACRRGMRELDISIMPFFEYEYDTLSDADKQLFIRLLENDDPDLFNWLMNHGKPADAELQRMVTLIQTRN
RERGPVAI
MDINNKARIHWACRRGMRELDISIMPFFEYEYDTLSDADKQLFIRLLENDDPDLFNWLMNHGKPADAELQRMVTLIQTRN
RERGPVAI
Download Length: 267 bp
>AT87812 NZ_CP024496:782757-783023 [Klebsiella pneumoniae]
ATGGACATTAACAATAAAGCACGTATCCACTGGGCATGCCGCCGCGGGATGCGCGAACTCGACATCTCCATCATGCCGTT
CTTTGAGTATGAGTACGATACCCTCAGCGACGCTGACAAACAGCTGTTCATTCGCCTGCTGGAAAATGACGATCCGGATC
TGTTCAACTGGCTGATGAACCACGGCAAACCGGCCGATGCGGAGCTGCAGCGGATGGTAACCTTAATTCAGACACGGAAT
CGGGAACGTGGTCCTGTGGCAATCTGA
ATGGACATTAACAATAAAGCACGTATCCACTGGGCATGCCGCCGCGGGATGCGCGAACTCGACATCTCCATCATGCCGTT
CTTTGAGTATGAGTACGATACCCTCAGCGACGCTGACAAACAGCTGTTCATTCGCCTGCTGGAAAATGACGATCCGGATC
TGTTCAACTGGCTGATGAACCACGGCAAACCGGCCGATGCGGAGCTGCAGCGGATGGTAACCTTAATTCAGACACGGAAT
CGGGAACGTGGTCCTGTGGCAATCTGA
Structures
Toxin
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Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A0H3GSW7 |
Antitoxin
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Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A0H3GY41 |