Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 185499..185770 Replicon chromosome
Accession NZ_CP024479
Organism Escherichia coli strain 2011C-4315

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 185629..185732 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 185499..185770 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
A5958_RS01170 182054..182716 - 663 WP_000944256.1 exodeoxyribonuclease X -
A5958_RS01175 182740..183396 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
A5958_RS01180 183498..183728 - 231 WP_000916763.1 DNA polymerase III subunit theta -
A5958_RS01185 183867..184241 + 375 WP_000204700.1 CopC domain-containing protein YobA -
A5958_RS01190 184245..185117 + 873 WP_000879280.1 copper homeostasis membrane protein CopD -
A5958_RS01195 185130..185471 + 342 WP_000976472.1 YebY family protein -
- 185499..185770 - 272 - - Antitoxin
- 185629..185732 + 104 - - Toxin
A5958_RS01200 185867..186523 + 657 WP_000812712.1 protein-serine/threonine phosphatase -
A5958_RS01205 186524..186715 - 192 WP_001296140.1 YebW family protein -
A5958_RS01210 186820..187056 - 237 WP_001295499.1 DUF1480 family protein -
A5958_RS01215 187174..188613 - 1440 WP_064460450.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T87754 NZ_CP024479:185629-185732 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT87754 NZ_CP024479:c185770-185499 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACATATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References