Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 3852755..3852989 | Replicon | chromosome |
| Accession | NZ_CP024473 | ||
| Organism | Shigella flexneri 7b strain 94-3007 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 3852756..3852859 (-) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 3852755..3852989 (+) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| CPZ98_RS19580 | 3848188..3848655 | - | 468 | Protein_3772 | DNA-binding transcriptional regulator PgrR | - |
| CPZ98_RS19585 | 3848719..3849029 | + | 311 | Protein_3773 | transposase | - |
| CPZ98_RS19590 | 3849072..3850281 | - | 1210 | Protein_3774 | IS3 family transposase | - |
| CPZ98_RS19595 | 3850336..3851184 | + | 849 | Protein_3775 | IS3-like element IS600 family transposase | - |
| CPZ98_RS19600 | 3851301..3851582 | + | 282 | WP_005127484.1 | excisionase | - |
| CPZ98_RS19605 | 3851548..3852624 | + | 1077 | Protein_3777 | phage integrase Arm DNA-binding domain-containing protein | - |
| - | 3852755..3852989 | + | 235 | - | - | Antitoxin |
| - | 3852756..3852859 | - | 104 | - | - | Toxin |
| CPZ98_RS19610 | 3853017..3853358 | - | 342 | WP_000976476.1 | YebY family protein | - |
| CPZ98_RS19615 | 3853371..3854243 | - | 873 | Protein_3779 | copper homeostasis membrane protein CopD | - |
| CPZ98_RS19620 | 3854247..3854621 | - | 375 | WP_000168747.1 | CopC domain-containing protein YobA | - |
| CPZ98_RS19625 | 3854760..3854990 | + | 231 | WP_000916763.1 | DNA polymerase III subunit theta | - |
| CPZ98_RS19630 | 3855092..3855748 | + | 657 | Protein_3782 | carbon-nitrogen hydrolase family protein YobB | - |
| CPZ98_RS19635 | 3855772..3856434 | + | 663 | WP_000944271.1 | exodeoxyribonuclease X | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 104 bp
>T87723 NZ_CP024473:c3852859-3852756 [Shigella flexneri 7b]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
Antitoxin
Download Length: 235 bp
>AT87723 NZ_CP024473:3852755-3852989 [Shigella flexneri 7b]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGCTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGCTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
