87686

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1061131..1061364 Replicon chromosome
Accession NZ_CP024466
Organism Shigella dysenteriae strain BU53M1

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1061261..1061364 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1061131..1061364 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CPZ97_RS05860 1057686..1058348 - 663 WP_000944256.1 exodeoxyribonuclease X -
CPZ97_RS05865 1058372..1059028 - 657 WP_000896381.1 carbon-nitrogen hydrolase family protein -
CPZ97_RS05870 1059130..1059360 - 231 WP_000916763.1 DNA polymerase III subunit theta -
CPZ97_RS05875 1059499..1059873 + 375 WP_000168738.1 CopC domain-containing protein YobA -
CPZ97_RS05880 1059877..1060749 + 873 WP_000879288.1 copper homeostasis membrane protein CopD -
CPZ97_RS05885 1060762..1061103 + 342 WP_134802023.1 YebY family protein -
- 1061131..1061364 - 234 - - Antitoxin
- 1061261..1061364 + 104 - - Toxin
CPZ97_RS05890 1061486..1061926 - 441 Protein_1103 tyrosine-type recombinase/integrase -
CPZ97_RS05900 1063205..1063901 + 697 Protein_1105 IS1 family transposase -
CPZ97_RS05905 1064016..1064297 - 282 WP_078164586.1 excisionase -
CPZ97_RS05915 1064449..1065144 + 696 Protein_1107 IS1-like element IS1N family transposase -
CPZ97_RS05920 1065336..1065521 + 186 WP_023637031.1 hypothetical protein -
CPZ97_RS05925 1065482..1065601 + 120 WP_001131442.1 hypothetical protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T87686 NZ_CP024466:1061261-1061364 [Shigella dysenteriae]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT

Antitoxin


Download         Length: 234 bp

>AT87686 NZ_CP024466:c1061364-1061131 [Shigella dysenteriae]
AAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCAT
TAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATA
AAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGTTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References