Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2767825..2767970 Replicon chromosome
Accession NZ_CP024458
Organism Klebsiella pneumoniae strain QS17-0161

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2767832..2767934 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2767825..2767970 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CR231_RS13860 2763357..2764790 + 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
CR231_RS13865 2764906..2765145 + 240 WP_002911393.1 YebV family protein -
CR231_RS13870 2765243..2765434 + 192 WP_002911395.1 YebW family protein -
CR231_RS13875 2765431..2766084 - 654 WP_009484457.1 protein-serine/threonine phosphatase -
CR231_RS13880 2766241..2767209 + 969 WP_014907334.1 VirK/YbjX family protein -
CR231_RS28940 2767314..2767457 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 2767825..2767970 + 146 - - Antitoxin
- 2767832..2767934 - 103 - - Toxin
CR231_RS13890 2768093..2768431 - 339 WP_002911404.1 YebY family protein -
CR231_RS13895 2768448..2769317 - 870 WP_004189267.1 copper homeostasis membrane protein CopD -
CR231_RS13900 2769321..2769695 - 375 WP_020316569.1 CopC domain-containing protein YobA -
CR231_RS13905 2769808..2770038 + 231 WP_002911406.1 DNA polymerase III subunit theta -
CR231_RS13910 2770117..2770776 + 660 WP_002911407.1 exodeoxyribonuclease X -
CR231_RS13915 2770780..2772840 - 2061 WP_032419805.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T87665 NZ_CP024458:c2767934-2767832 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT87665 NZ_CP024458:2767825-2767970 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References