Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-yefM/YoeB-RelB
Location 1648957..1649476 Replicon chromosome
Accession NZ_CP024443
Organism Moraxella osloensis strain NP7

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag NP7_RS07320 Protein ID WP_199488842.1
Coordinates 1648957..1649223 (-) Length 89 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag NP7_RS07325 Protein ID WP_100270297.1
Coordinates 1649213..1649476 (-) Length 88 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NP7_RS07310 1646815..1648239 + 1425 WP_100270294.1 cytochrome c oxidase accessory protein CcoG -
NP7_RS07315 1648366..1648935 + 570 WP_100270295.1 FixH family protein -
NP7_RS07320 1648957..1649223 - 267 WP_199488842.1 Txe/YoeB family addiction module toxin Toxin
NP7_RS07325 1649213..1649476 - 264 WP_100270297.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
NP7_RS07330 1649531..1650256 - 726 WP_100270298.1 hypothetical protein -
NP7_RS07335 1650253..1651116 - 864 WP_199488983.1 PHP domain-containing protein -
NP7_RS07340 1651383..1651946 + 564 WP_100270300.1 septation protein IspZ -
NP7_RS07345 1651959..1652261 + 303 WP_100270301.1 hypothetical protein -
NP7_RS07350 1652327..1652755 + 429 WP_100270302.1 hypothetical protein -
NP7_RS07355 1652824..1654080 + 1257 WP_199488984.1 TIGR03862 family flavoprotein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(10-87)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(3-73)


Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10463.09 Da        Isoelectric Point: 9.4407

>T87658 WP_199488842.1 NZ_CP024443:c1649223-1648957 [Moraxella osloensis]
MMSRSINFVPIAWEQYLYWQGQDRKTLKRINLLIKDIIRSPFAGIGKPEALKENLSGYWSRRIDETNRLVYAVEDNQIVI
IGCRFHYD

Download         Length: 267 bp

>T87658 NZ_CP024443:c1649223-1648957 [Moraxella osloensis]
ATGATGAGTAGGTCAATCAATTTTGTACCAATAGCATGGGAGCAGTACTTGTATTGGCAAGGACAAGACAGAAAGACTTT
AAAACGTATCAACTTATTAATTAAGGATATCATCCGCTCGCCATTTGCAGGTATTGGCAAACCCGAAGCCTTAAAAGAGA
ATTTGTCTGGCTATTGGTCAAGACGAATTGATGAGACTAATCGGTTAGTGTATGCGGTTGAAGACAATCAAATTGTCATT
ATCGGTTGTCGCTTCCATTATGATTAA

Antitoxin


Download         Length: 88 a.a.        Molecular weight: 9846.08 Da        Isoelectric Point: 5.6863

>AT87658 WP_100270297.1 NZ_CP024443:c1649476-1649213 [Moraxella osloensis]
MYVESYSDVRANLKAVIDRTINDAEITLIHRKQGGNAVLMSEDYFNSLQETFYLNSTTANKKALEQAIAQHKAGKALKRN
LLEIDDE

Download         Length: 264 bp

>AT87658 NZ_CP024443:c1649476-1649213 [Moraxella osloensis]
ATGTATGTCGAAAGCTACAGCGATGTACGCGCCAATCTAAAAGCCGTCATCGACCGCACCATCAACGATGCGGAAATCAC
CTTAATTCATCGCAAACAAGGCGGTAATGCAGTCTTGATGAGCGAAGATTATTTTAATAGCTTACAAGAGACTTTTTATC
TTAACTCAACCACAGCCAACAAAAAAGCACTCGAACAAGCTATTGCGCAACATAAAGCAGGCAAAGCGCTCAAACGCAAT
TTGCTAGAGATTGATGATGAGTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References