Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3295675..3295820 Replicon chromosome
Accession NZ_CP024429
Organism Klebsiella pneumoniae strain DA48896

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3295682..3295784 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3295675..3295820 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BKL84_RS16510 3291206..3292639 + 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
BKL84_RS16515 3292755..3292994 + 240 WP_002911393.1 YebV family protein -
BKL84_RS16520 3293092..3293283 + 192 WP_002911395.1 YebW family protein -
BKL84_RS16525 3293280..3293933 - 654 WP_024622748.1 protein-serine/threonine phosphatase -
BKL84_RS16530 3294090..3295058 + 969 WP_014907334.1 VirK/YbjX family protein -
BKL84_RS29400 3295163..3295306 + 144 WP_038431282.1 Ecr family regulatory small membrane protein -
- 3295675..3295820 + 146 - - Antitoxin
- 3295682..3295784 - 103 - - Toxin
BKL84_RS16540 3295943..3296281 - 339 WP_002911404.1 YebY family protein -
BKL84_RS16545 3296298..3297167 - 870 WP_004175431.1 copper homeostasis membrane protein CopD -
BKL84_RS16550 3297171..3297545 - 375 WP_039819395.1 CopC domain-containing protein YobA -
BKL84_RS16555 3297658..3297888 + 231 WP_002911406.1 DNA polymerase III subunit theta -
BKL84_RS16560 3297967..3298626 + 660 WP_002911407.1 exodeoxyribonuclease X -
BKL84_RS16565 3298630..3300690 - 2061 WP_004151449.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T87638 NZ_CP024429:c3295784-3295682 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT87638 NZ_CP024429:3295675-3295820 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References