Detailed information of TA system TA087627

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): BrnTA/BrnT-BrnA
• Location: 1817759..1818276
• Replicon: chromosome
• Accession: NZ_CP024422
• Organism: Paracoccus yeei strain TT13

Toxin (Protein)

• Gene name: brnT
• Uniprot ID: -
• Locus tag: PYTT13_RS09145
• Protein ID: WP_099648896.1
• Coordinates: 1818028..1818276 (-)
• Length: 83 a.a.

Antitoxin (Protein)

• Gene name: brnA
• Uniprot ID: -
• Locus tag: PYTT13_RS09140
• Protein ID: WP_099648895.1
• Coordinates: 1817759..1818031 (-)
• Length: 91 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
PYTT13_RS09125	1812783..1813559	+	777	WP_157767323.1	hypothetical protein	-
PYTT13_RS22755	1813777..1814205	+	429	WP_157767324.1	hypothetical protein	-
PYTT13_RS23125	1814486..1814917	+	432	WP_191569402.1	hypothetical protein	-
PYTT13_RS09130	1814919..1817423	+	2505	WP_198406614.1	tape measure protein	-
PYTT13_RS09140	1817759..1818031	-	273	WP_099648895.1	BrnA antitoxin family protein	Antitoxin
PYTT13_RS09145	1818028..1818276	-	249	WP_099648896.1	BrnT family toxin	Toxin
PYTT13_RS09155	1818668..1819753	+	1086	WP_099650066.1	NUDIX domain-containing protein	-
PYTT13_RS09160	1819830..1820861	+	1032	WP_099648897.1	cysteine synthase A	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Ribonuclease toxin, BrnT, of type II toxin-antitoxin system (6-78)

Antitoxin

• BrnA antitoxin of type II toxin-antitoxin system (15-88)

Sequences

Toxin

Protein

• Length: 83 a.a.
• Molecular weight: 8956.44 Da
• Isoelectric Point: 7.2033

>T87627 WP_099648896.1 NZ_CP024422:c1818276-1818028 [Paracoccus yeei]
MTMIVWDEPKRLTNLAKHGLDFADLDEQFFLASVVVPAKGGRHMAIGRMADGTIAVVFATLGTEGVSVISMRPASQRERN
LL

Nucleotide

• Length: 249 bp

>T87627 NZ_CP024422:c1818276-1818028 [Paracoccus yeei]
ATGACGATGATCGTATGGGACGAACCGAAGCGGCTGACGAACCTTGCCAAGCATGGTTTGGACTTCGCCGATCTGGATGA
ACAGTTCTTTCTGGCATCGGTCGTCGTCCCGGCGAAGGGTGGTCGTCACATGGCGATAGGCCGCATGGCTGACGGCACGA
TTGCCGTGGTGTTCGCAACGCTGGGCACGGAAGGCGTATCGGTCATTTCGATGCGGCCCGCCAGCCAAAGGGAAAGGAAC
CTGCTATGA

Antitoxin

Protein

• Length: 91 a.a.
• Molecular weight: 9790.09 Da
• Isoelectric Point: 8.7856

>AT87627 WP_099648895.1 NZ_CP024422:c1818031-1817759 [Paracoccus yeei]
MTEEQIQRMIASDPDAPEATDEQLAQARPFTEAFPALADAMRKNAGGRPKSANPKVAVSLRLDQDVVARFKASGPGWQSR
INAVLREAKV

Nucleotide

• Length: 273 bp

>AT87627 NZ_CP024422:c1818031-1817759 [Paracoccus yeei]
ATGACCGAAGAACAGATTCAGCGGATGATTGCCAGCGATCCTGACGCGCCGGAAGCGACGGACGAACAGCTTGCACAGGC
GCGCCCGTTCACCGAAGCGTTCCCCGCCCTGGCCGATGCGATGCGCAAGAACGCCGGGGGCCGTCCGAAATCGGCCAACC
CGAAAGTTGCCGTGTCGCTGCGGCTGGATCAGGACGTTGTGGCGCGGTTCAAGGCCAGCGGGCCGGGCTGGCAGTCCAGA
ATCAACGCGGTGCTGCGGGAAGCGAAGGTTTAA