Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/ParE-RHH
Location 1749691..1750231 Replicon chromosome
Accession NZ_CP024422
Organism Paracoccus yeei strain TT13

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag PYTT13_RS08730 Protein ID WP_099648840.1
Coordinates 1749938..1750231 (+) Length 98 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag PYTT13_RS08725 Protein ID WP_099648839.1
Coordinates 1749691..1749948 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PYTT13_RS08700 1745095..1745496 + 402 WP_099648835.1 hypothetical protein -
PYTT13_RS08705 1745542..1746522 + 981 WP_099648836.1 DUF1775 domain-containing protein -
PYTT13_RS08710 1746509..1747126 + 618 WP_028718050.1 SCO family protein -
PYTT13_RS08715 1747391..1748254 + 864 WP_099648837.1 hypothetical protein -
PYTT13_RS08720 1748238..1749596 + 1359 WP_099648838.1 plasmid recombination protein -
PYTT13_RS08725 1749691..1749948 + 258 WP_099648839.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
PYTT13_RS08730 1749938..1750231 + 294 WP_099648840.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PYTT13_RS08735 1750321..1750566 - 246 WP_198406709.1 type II toxin-antitoxin system ParD family antitoxin -
PYTT13_RS08740 1750770..1750955 + 186 WP_099648842.1 hypothetical protein -
PYTT13_RS08745 1751175..1752348 - 1174 Protein_1722 ATP-binding protein -
PYTT13_RS08750 1752677..1752880 - 204 WP_099648843.1 hypothetical protein -
PYTT13_RS08755 1752880..1753386 - 507 WP_099648844.1 hypothetical protein -
PYTT13_RS08760 1753383..1753565 - 183 WP_099648845.1 hypothetical protein -
PYTT13_RS08765 1753562..1753885 - 324 WP_099648846.1 zinc ribbon domain-containing protein -
PYTT13_RS08770 1753995..1754240 + 246 WP_099648847.1 helix-turn-helix domain-containing protein -
PYTT13_RS08775 1754470..1754607 - 138 Protein_1728 IS3 family transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(7-92)

Antitoxin

Antitoxin ParD

(4-72)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 11090.64 Da        Isoelectric Point: 8.5129

>T87626 WP_099648840.1 NZ_CP024422:1749938-1750231 [Paracoccus yeei]
MTTKAWRLSPLAEDDLEGIWLYTMRHWSVAQADNYYRQLVAEIEALAAGRTRGRSCTVRAGYLKRSCGSHVIFFRDLGNT
LDIVRILHGAQDAERHL

Download         Length: 294 bp

>T87626 NZ_CP024422:1749938-1750231 [Paracoccus yeei]
ATGACAACTAAGGCCTGGCGTCTTTCGCCACTGGCCGAGGACGATCTGGAAGGTATCTGGCTTTACACGATGCGGCATTG
GTCCGTGGCGCAGGCCGACAACTATTACCGGCAGCTGGTGGCCGAAATCGAGGCGCTGGCGGCGGGCAGGACGCGAGGCC
GGAGCTGCACCGTCCGGGCAGGTTATCTCAAGCGCAGCTGCGGATCGCATGTTATCTTTTTCCGCGATCTGGGCAACACG
CTGGATATCGTCCGCATCCTGCACGGTGCGCAGGACGCCGAGCGGCATCTGTGA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9319.33 Da        Isoelectric Point: 5.9672

>AT87626 WP_099648839.1 NZ_CP024422:1749691-1749948 [Paracoccus yeei]
MARNTSVSLGDHFVDFIDAQVKGGRYGSASDVVRAGLRLLEEHEAKVQALEAALIAGEESGEARPFDSEAFLTRMHTRHV
ARHDN

Download         Length: 258 bp

>AT87626 NZ_CP024422:1749691-1749948 [Paracoccus yeei]
ATGGCCCGGAATACATCGGTTTCGCTTGGCGACCACTTTGTCGATTTCATCGACGCTCAGGTGAAGGGCGGTCGTTACGG
CTCGGCCAGCGATGTGGTGCGGGCGGGGCTGCGGCTGCTGGAAGAGCATGAGGCCAAGGTGCAGGCTTTGGAAGCTGCCC
TGATCGCCGGAGAGGAATCGGGCGAGGCGCGCCCGTTCGACTCCGAGGCGTTCCTGACCCGGATGCACACCAGGCACGTC
GCCCGGCATGACAACTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References