Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 800869..801539 Replicon chromosome
Accession NZ_CP024422
Organism Paracoccus yeei strain TT13

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag PYTT13_RS03925 Protein ID WP_099648264.1
Coordinates 800869..801303 (-) Length 145 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag PYTT13_RS03930 Protein ID WP_099650018.1
Coordinates 801300..801539 (-) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PYTT13_RS03895 796071..796526 - 456 WP_099648260.1 DUF2924 domain-containing protein -
PYTT13_RS03905 796855..798285 + 1431 WP_099648262.1 hypothetical protein -
PYTT13_RS03910 798298..799524 - 1227 WP_099647977.1 IS256 family transposase -
PYTT13_RS03915 799831..800070 + 240 WP_099648263.1 hypothetical protein -
PYTT13_RS03920 800165..800878 + 714 Protein_771 sigma-70 family RNA polymerase sigma factor -
PYTT13_RS03925 800869..801303 - 435 WP_099648264.1 type II toxin-antitoxin system VapC family toxin Toxin
PYTT13_RS03930 801300..801539 - 240 WP_099650018.1 plasmid stabilization protein Antitoxin
PYTT13_RS03935 801663..801863 + 201 WP_099648265.1 hypothetical protein -
PYTT13_RS03940 801860..804085 + 2226 WP_099648266.1 AAA family ATPase -
PYTT13_RS03945 804419..804619 + 201 WP_099650019.1 hypothetical protein -
PYTT13_RS03950 804612..804989 + 378 WP_099648267.1 RNA polymerase subunit sigma -
PYTT13_RS03955 805131..805487 + 357 WP_099648268.1 HNH endonuclease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- flank IS/Tn - - 798298..799524 1226


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-122)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 145 a.a.        Molecular weight: 15619.01 Da        Isoelectric Point: 4.8999

>T87625 WP_099648264.1 NZ_CP024422:c801303-800869 [Paracoccus yeei]
MIILDTNVVSETMKPVPEPRVIDWLNRQELSTLHLTTVSLAELRFGMARLEPGRRRDDFGLRLERMLTEVFPGRVLGFDA
AAANAFGALVSLAERHGRTVSFPDGAIAAIAAANGYPVATRDVAPFIAMGVDVVDPWDPIPPGP

Download         Length: 435 bp

>T87625 NZ_CP024422:c801303-800869 [Paracoccus yeei]
ATGATCATCCTCGATACGAACGTCGTCTCGGAGACGATGAAGCCGGTCCCCGAGCCGCGGGTGATCGACTGGCTCAACCG
CCAGGAGCTGAGCACCCTGCACCTGACCACCGTCAGCCTGGCCGAGTTGCGGTTCGGCATGGCGCGGCTCGAGCCCGGCC
GCCGCCGGGATGATTTCGGGCTTCGGCTCGAGCGGATGCTGACGGAGGTCTTTCCCGGCAGGGTCCTGGGGTTCGACGCA
GCTGCGGCGAATGCCTTTGGCGCGCTCGTCTCGCTGGCGGAGCGGCACGGGCGGACGGTGAGCTTCCCGGACGGCGCGAT
CGCCGCCATCGCTGCGGCGAACGGCTATCCCGTCGCCACCCGCGATGTCGCGCCGTTCATCGCCATGGGCGTGGACGTCG
TCGATCCGTGGGACCCGATCCCTCCTGGCCCATGA

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 8625.87 Da        Isoelectric Point: 6.4573

>AT87625 WP_099650018.1 NZ_CP024422:c801539-801300 [Paracoccus yeei]
MAQIVVRQIPDEVHRALKAQAAAHGRSAEAELREIIARAVLPQSLARAGDLMRGIWSGATMDGFSVERDRTPVEPACFE

Download         Length: 240 bp

>AT87625 NZ_CP024422:c801539-801300 [Paracoccus yeei]
ATGGCCCAGATCGTCGTGCGACAGATCCCCGACGAGGTGCATCGCGCCCTGAAGGCGCAGGCGGCCGCCCATGGCCGGAG
CGCGGAGGCTGAGCTCCGCGAGATCATTGCCCGTGCAGTCCTGCCCCAGTCTCTCGCGCGCGCGGGCGATCTGATGCGCG
GCATCTGGTCAGGCGCCACGATGGACGGGTTCTCAGTCGAGCGCGACCGCACCCCCGTGGAGCCGGCCTGCTTCGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References