Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-RelB
Location 172217..172815 Replicon plasmid pRspNXC24a
Accession NZ_CP024312
Organism Rhizobium sp. NXC24

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag NXC24_RS21210 Protein ID WP_104825436.1
Coordinates 172522..172815 (+) Length 98 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag NXC24_RS21205 Protein ID WP_104825435.1
Coordinates 172217..172525 (+) Length 103 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NXC24_RS21180 167715..168032 + 318 WP_104825537.1 hypothetical protein -
NXC24_RS21185 168029..170299 + 2271 WP_104825431.1 relaxase/mobilization nuclease domain-containing protein -
NXC24_RS21190 170430..170660 + 231 WP_104825432.1 hypothetical protein -
NXC24_RS21195 170732..171628 + 897 WP_104825433.1 Fic family protein -
NXC24_RS21200 171759..171989 - 231 WP_104825434.1 hypothetical protein -
NXC24_RS21205 172217..172525 + 309 WP_104825435.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
NXC24_RS21210 172522..172815 + 294 WP_104825436.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NXC24_RS21215 172875..175229 - 2355 WP_104825437.1 type IV secretory system conjugative DNA transfer family protein -
NXC24_RS21220 175207..176253 - 1047 WP_104825438.1 P-type DNA transfer ATPase VirB11 -
NXC24_RS21225 176219..177574 - 1356 WP_104825439.1 type IV secretion system protein VirB10 -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..271356 271356


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-90)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-53)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 10583.03 Da        Isoelectric Point: 5.6864

>T87610 WP_104825436.1 NZ_CP024312:172522-172815 [Rhizobium sp. NXC24]
MKLIWSAFALADRDGIFTHIEADNPAAAASVDERIAAAARRLRDFPESGRPGRIAGTRELVITGTPYIAAYVVTETAVRI
LRVLHGAQQWPEALPED

Download         Length: 294 bp

>T87610 NZ_CP024312:172522-172815 [Rhizobium sp. NXC24]
TTGAAGCTCATCTGGTCCGCCTTCGCGCTCGCCGATCGCGATGGCATCTTCACCCATATTGAGGCCGACAATCCGGCCGC
CGCCGCCTCGGTCGACGAACGGATTGCGGCCGCGGCCCGTCGTCTGCGGGATTTTCCGGAGAGCGGCCGTCCCGGCAGGA
TTGCCGGGACACGCGAGTTGGTGATTACCGGCACGCCTTATATCGCTGCCTATGTCGTGACGGAAACTGCAGTCCGCATT
CTCCGTGTCCTGCACGGCGCGCAGCAATGGCCCGAAGCTTTGCCCGAAGACTGA

Antitoxin


Download         Length: 103 a.a.        Molecular weight: 11079.48 Da        Isoelectric Point: 5.1771

>AT87610 WP_104825435.1 NZ_CP024312:172217-172525 [Rhizobium sp. NXC24]
MAANALVQTRIDSSVRDRASAVLESMGLTVSDAVRILLTRTANEGALPLELVTGSEAHDAWFRGKVLEALNDTRPDIPDD
EVEAHFAERRAAARRKAADLKP

Download         Length: 309 bp

>AT87610 NZ_CP024312:172217-172525 [Rhizobium sp. NXC24]
ATGGCTGCAAATGCTCTCGTTCAAACCCGCATTGATTCCTCGGTTCGGGATCGTGCATCCGCCGTGCTCGAAAGCATGGG
GCTGACGGTTTCCGATGCCGTGCGGATCCTGCTCACCCGGACCGCCAATGAAGGTGCACTGCCGCTCGAACTGGTGACTG
GCAGCGAGGCGCATGATGCCTGGTTCCGGGGCAAGGTGCTGGAGGCGCTGAACGATACGCGGCCCGATATCCCCGATGAT
GAGGTCGAAGCACACTTTGCGGAGCGGCGCGCGGCGGCACGCCGTAAGGCAGCCGACCTGAAACCTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References