87608

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-Phd
Location 3056957..3057621 Replicon chromosome
Accession NZ_CP024311
Organism Rhizobium sp. NXC24

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag NXC24_RS15155 Protein ID WP_104824051.1
Coordinates 3057211..3057621 (+) Length 137 a.a.

Antitoxin (Protein)


Gene name vapC Uniprot ID -
Locus tag NXC24_RS15150 Protein ID WP_104824050.1
Coordinates 3056957..3057211 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NXC24_RS15120 3052469..3053050 + 582 WP_104824045.1 NAD(P)H-dependent oxidoreductase -
NXC24_RS15125 3053094..3053483 - 390 WP_104825181.1 enamine deaminase RidA -
NXC24_RS15130 3053596..3054492 - 897 WP_104824046.1 DMT family transporter -
NXC24_RS15135 3054692..3055129 + 438 WP_104824047.1 hypothetical protein -
NXC24_RS15140 3055161..3055778 - 618 WP_104824048.1 alpha/beta hydrolase -
NXC24_RS15145 3055792..3056724 - 933 WP_104824049.1 VOC family protein -
NXC24_RS15150 3056957..3057211 + 255 WP_104824050.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
NXC24_RS15155 3057211..3057621 + 411 WP_104824051.1 type II toxin-antitoxin system VapC family toxin Toxin
NXC24_RS15160 3057615..3058316 - 702 WP_104824052.1 uracil-DNA glycosylase -
NXC24_RS15165 3058406..3059047 - 642 WP_104824053.1 septation protein IspZ -
NXC24_RS15170 3059135..3061582 - 2448 WP_104824054.1 FAD-dependent oxidoreductase -
NXC24_RS15175 3061592..3062470 - 879 WP_104824055.1 phosphotransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-116)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(3-63)


Sequences

Toxin        


Download         Length: 137 a.a.        Molecular weight: 15170.31 Da        Isoelectric Point: 6.4860

>T87608 WP_104824051.1 NZ_CP024311:3057211-3057621 [Rhizobium sp. NXC24]
MYLIDTNIISEARRGTIEAISWLRTADPSTVYLSVITLGEVMRGIALKRRTDPRAAAHLEEWLRKLRHDHSGRILPITDQ
IAVEWGRIAALRPRGDADGLIAATAIVHDLIVVTRNVSDFDDTGVSVINPWDQASY

Download         Length: 411 bp

>T87608 NZ_CP024311:3057211-3057621 [Rhizobium sp. NXC24]
ATGTATCTGATCGATACCAATATCATTTCTGAAGCGCGTCGCGGCACTATCGAAGCGATATCCTGGCTGCGCACAGCCGA
CCCATCGACCGTCTATCTCAGCGTCATCACACTCGGCGAAGTCATGCGCGGGATCGCCCTTAAGCGAAGGACCGATCCAC
GCGCCGCCGCACATCTGGAAGAATGGCTGCGCAAGCTTCGCCACGATCACAGCGGCCGCATCCTGCCCATCACGGACCAA
ATCGCCGTCGAATGGGGCCGCATCGCCGCGCTACGTCCTCGCGGCGATGCCGACGGGCTGATCGCGGCCACTGCAATCGT
CCATGATCTGATTGTCGTTACGCGCAATGTCAGCGATTTTGACGATACCGGCGTGTCGGTGATCAATCCTTGGGATCAGG
CATCTTACTGA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9216.26 Da        Isoelectric Point: 4.4165

>AT87608 WP_104824050.1 NZ_CP024311:3056957-3057211 [Rhizobium sp. NXC24]
MDWPLQDAKNQFSKVVQKARSEGPQTVTLRGERAVVVLSAEDYDALRAGKPSLVDDLLSGPAWDDELADAVTTRDKTPSR
DVAF

Download         Length: 255 bp

>AT87608 NZ_CP024311:3056957-3057211 [Rhizobium sp. NXC24]
ATGGATTGGCCATTGCAAGACGCCAAGAATCAATTCTCGAAAGTCGTGCAGAAGGCACGCAGCGAAGGTCCGCAAACTGT
GACACTGCGCGGCGAGCGCGCGGTCGTTGTTCTCTCCGCGGAAGACTATGACGCCTTGCGCGCGGGAAAGCCGAGCCTAG
TGGACGATCTGCTATCGGGGCCAGCCTGGGATGATGAGCTGGCCGACGCGGTGACAACGCGAGACAAGACCCCAAGCCGG
GATGTCGCCTTCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References