87605

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/upstrm_HI1419-dnstrm_HI1420
Location 1062793..1063370 Replicon chromosome
Accession NZ_CP024311
Organism Rhizobium sp. NXC24

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag NXC24_RS05315 Protein ID WP_104822357.1
Coordinates 1063080..1063370 (-) Length 97 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag NXC24_RS05310 Protein ID WP_104822356.1
Coordinates 1062793..1063077 (-) Length 95 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NXC24_RS05295 1059651..1060649 + 999 WP_104822353.1 NAD(P)H-quinone oxidoreductase -
NXC24_RS05300 1060630..1062057 - 1428 WP_104822354.1 MFS transporter -
NXC24_RS05305 1062159..1062782 + 624 WP_104822355.1 MarR family transcriptional regulator -
NXC24_RS05310 1062793..1063077 - 285 WP_104822356.1 putative addiction module antidote protein Antitoxin
NXC24_RS05315 1063080..1063370 - 291 WP_104822357.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NXC24_RS05320 1063550..1064557 + 1008 WP_104822358.1 asparaginase -
NXC24_RS05325 1064604..1065365 - 762 WP_104825017.1 DeoR/GlpR family DNA-binding transcription regulator -
NXC24_RS05330 1065488..1065844 + 357 WP_104822359.1 DUF4406 domain-containing protein -
NXC24_RS05335 1065984..1066604 + 621 WP_104822360.1 glutathione S-transferase N-terminal domain-containing protein -
NXC24_RS05340 1066605..1066961 - 357 WP_104825018.1 MmcQ/YjbR family DNA-binding protein -
NXC24_RS05345 1067080..1067265 - 186 WP_104822361.1 hypothetical protein -
NXC24_RS05350 1067413..1068309 + 897 WP_104822362.1 LysR family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(1-95)

Antitoxin

Cro/C1-type helix-turn-helix domain

(46-90)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 10666.35 Da        Isoelectric Point: 9.7931

>T87605 WP_104822357.1 NZ_CP024311:c1063370-1063080 [Rhizobium sp. NXC24]
MIEIRQTAEFAEWLGKIKDINAVARIQVRIRRLSLGNPGDVKPVGEGISELRIDYGPGYRLYYHKRGQELVLLLCGGDKS
TQNADIAKAKALAKEA

Download         Length: 291 bp

>T87605 NZ_CP024311:c1063370-1063080 [Rhizobium sp. NXC24]
ATGATCGAAATCCGTCAGACCGCTGAGTTCGCTGAGTGGCTTGGCAAAATCAAAGATATCAACGCGGTTGCTCGTATCCA
GGTGAGGATTCGTCGCCTCTCGCTTGGAAATCCCGGCGATGTAAAGCCTGTCGGCGAAGGCATCAGCGAACTTCGCATCG
ATTACGGCCCGGGATATCGGCTTTACTATCATAAACGCGGCCAGGAACTCGTTCTGCTCCTATGCGGTGGCGACAAGAGC
ACTCAGAACGCCGATATTGCAAAGGCTAAAGCACTCGCGAAGGAGGCTTGA

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 9883.22 Da        Isoelectric Point: 4.4488

>AT87605 WP_104822356.1 NZ_CP024311:c1063077-1062793 [Rhizobium sp. NXC24]
MALETKPWDPTEHLDSPEAIAAYVEAAFEDGDPALIAAVIGDVARARGMTQLAKEAGVSRETIYKAFSEGGNPTLETLSG
VIRALGLKLTVRAA

Download         Length: 285 bp

>AT87605 NZ_CP024311:c1063077-1062793 [Rhizobium sp. NXC24]
ATGGCACTCGAAACCAAACCTTGGGATCCGACGGAACATCTGGACAGTCCTGAAGCCATTGCAGCCTATGTCGAAGCGGC
ATTCGAGGACGGCGACCCTGCACTTATTGCCGCAGTCATCGGTGACGTCGCCCGTGCCCGCGGCATGACGCAGCTCGCAA
AGGAAGCCGGGGTCAGCCGCGAAACGATCTACAAGGCCTTCAGCGAAGGCGGTAATCCGACACTGGAAACGCTATCAGGC
GTCATTCGCGCTCTCGGTTTGAAATTGACTGTACGGGCAGCATAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References