Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pasABC/RelE-HTH
Location 805832..806312 Replicon chromosome
Accession NZ_CP024311
Organism Rhizobium sp. NXC24

Toxin (Protein)


Gene name pasB Uniprot ID -
Locus tag NXC24_RS03955 Protein ID WP_104822116.1
Coordinates 805832..806101 (-) Length 90 a.a.

Antitoxin (Protein)


Gene name pasA Uniprot ID -
Locus tag NXC24_RS03960 Protein ID WP_104822117.1
Coordinates 806085..806312 (-) Length 76 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NXC24_RS03930 801759..802808 + 1050 WP_104822111.1 aldo/keto reductase -
NXC24_RS03935 802854..803879 - 1026 WP_104822112.1 NAD(P)-dependent alcohol dehydrogenase -
NXC24_RS03940 803990..804892 + 903 WP_104822113.1 LysR family transcriptional regulator -
NXC24_RS03945 804893..805168 + 276 WP_104822114.1 hypothetical protein -
NXC24_RS03950 805226..805774 - 549 WP_104822115.1 2'-5' RNA ligase family protein -
NXC24_RS03955 805832..806101 - 270 WP_104822116.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NXC24_RS03960 806085..806312 - 228 WP_104822117.1 TraY domain-containing protein Antitoxin
NXC24_RS03965 806479..808002 + 1524 WP_104822118.1 histidine--tRNA ligase -
NXC24_RS03970 808159..809277 + 1119 WP_104822119.1 ATP phosphoribosyltransferase regulatory subunit -
NXC24_RS03975 809277..809972 + 696 WP_104822120.1 ATP phosphoribosyltransferase -
NXC24_RS03980 810053..810496 - 444 WP_104822121.1 DoxX family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-88)

Antitoxin

Relaxosome protein TraY

(7-50)


Sequences

Toxin        


Download         Length: 90 a.a.        Molecular weight: 10689.30 Da        Isoelectric Point: 10.2777

>T87604 WP_104822116.1 NZ_CP024311:c806101-805832 [Rhizobium sp. NXC24]
VVWTIEYARSARKFVEKLDPKTRRRIRDFLEERLPSLHDPRQVGDALQGAKLGNYWRYRVGDYRIICDLQDSRLVVLVVE
IGNRRDIYR

Download         Length: 270 bp

>T87604 NZ_CP024311:c806101-805832 [Rhizobium sp. NXC24]
GTGGTCTGGACGATTGAGTACGCCCGATCTGCTCGCAAATTCGTTGAAAAACTCGACCCAAAGACACGCAGGAGAATAAG
GGACTTTCTGGAAGAGCGTCTTCCGAGCCTGCACGATCCGCGCCAGGTCGGCGACGCTTTGCAAGGTGCAAAACTCGGAA
ACTATTGGCGTTATCGGGTTGGCGACTATCGGATCATTTGCGATCTGCAGGATAGCCGGCTGGTCGTGTTAGTCGTCGAA
ATCGGCAACCGTCGCGACATCTATCGTTGA

Antitoxin


Download         Length: 76 a.a.        Molecular weight: 8820.82 Da        Isoelectric Point: 4.4290

>AT87604 WP_104822117.1 NZ_CP024311:c806312-806085 [Rhizobium sp. NXC24]
MSKQTAIRLPDETYERLQALAERTGRTATYYIRQAIEAHLQDLEDVYLAERAMERIKKGEDEIVSSEEFWRGLDD

Download         Length: 228 bp

>AT87604 NZ_CP024311:c806312-806085 [Rhizobium sp. NXC24]
ATGAGCAAGCAGACAGCTATCCGTTTGCCAGATGAGACCTATGAGCGCCTACAGGCTCTGGCCGAACGCACCGGTCGTAC
AGCAACCTACTATATCCGGCAGGCGATTGAAGCACATCTGCAGGACCTGGAGGACGTGTATTTGGCTGAGCGGGCCATGG
AGCGGATTAAGAAGGGCGAAGACGAGATCGTAAGCTCCGAGGAGTTCTGGCGTGGTCTGGACGATTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References