Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 421285..421928 Replicon chromosome
Accession NZ_CP024311
Organism Rhizobium sp. NXC24

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag NXC24_RS02095 Protein ID WP_104821786.1
Coordinates 421285..421689 (-) Length 135 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag NXC24_RS02100 Protein ID WP_104821787.1
Coordinates 421686..421928 (-) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NXC24_RS02060 416382..417287 + 906 WP_104821779.1 LysR family transcriptional regulator -
NXC24_RS02065 417288..418163 - 876 WP_104821780.1 LysR family transcriptional regulator -
NXC24_RS02070 418260..419543 + 1284 WP_104821781.1 MFS transporter -
NXC24_RS02075 419566..419952 + 387 WP_104821782.1 VOC family protein -
NXC24_RS02080 420071..420412 + 342 WP_104821783.1 metalloregulator ArsR/SmtB family transcription factor -
NXC24_RS02085 420396..420878 + 483 WP_104821784.1 SRPBCC domain-containing protein -
NXC24_RS02090 420884..421288 + 405 WP_104821785.1 GFA family protein -
NXC24_RS02095 421285..421689 - 405 WP_104821786.1 type II toxin-antitoxin system VapC family toxin Toxin
NXC24_RS02100 421686..421928 - 243 WP_104821787.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
NXC24_RS02105 421994..422668 - 675 WP_104821788.1 hypothetical protein -
NXC24_RS02110 422794..424455 - 1662 WP_104821789.1 urocanate hydratase -
NXC24_RS02115 424498..424827 - 330 WP_104821790.1 cold-shock protein -
NXC24_RS02120 424846..425946 - 1101 WP_104821791.1 DUF917 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(3-122)

Antitoxin

SpoVT-AbrB domain

(7-44)


Sequences

Toxin        


Download         Length: 135 a.a.        Molecular weight: 15055.16 Da        Isoelectric Point: 6.4885

>T87603 WP_104821786.1 NZ_CP024311:c421689-421285 [Rhizobium sp. NXC24]
VKYLLDSNAVIALMKGHTGFVSELRRHKPQDFAISAIVAHELFYGAYKGQRVADNLVRVDALQFETLDFDREDARVAGEI
RANLASLGTPIGAYDVLIAGQAVARDLILITRNVREFERVHKLRFEDWESLPSS

Download         Length: 405 bp

>T87603 NZ_CP024311:c421689-421285 [Rhizobium sp. NXC24]
GTGAAGTATTTGCTCGATAGCAATGCTGTCATCGCTCTGATGAAAGGGCATACCGGCTTCGTGAGCGAGCTTCGCAGACA
CAAGCCGCAGGATTTCGCCATCTCGGCCATCGTCGCGCACGAATTGTTTTATGGTGCCTATAAGGGGCAGCGTGTTGCAG
ACAATCTTGTGCGTGTCGATGCTTTGCAATTCGAGACACTGGATTTCGATAGGGAAGATGCCCGCGTGGCGGGCGAAATT
CGTGCCAACTTGGCTTCGCTCGGCACGCCAATCGGTGCCTATGACGTTTTGATCGCGGGTCAGGCAGTCGCCCGCGATCT
GATCCTGATAACGCGCAACGTCAGGGAATTTGAGCGCGTTCACAAGCTACGTTTCGAAGACTGGGAGTCCTTGCCGAGTA
GCTAA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 9337.45 Da        Isoelectric Point: 4.3430

>AT87603 WP_104821787.1 NZ_CP024311:c421928-421686 [Rhizobium sp. NXC24]
MDTAKIFWSGRSQAIRLPKEFRLDGEEVRIRRQGKAIILEPIAEDWDWLESVTGPVDHDFEEAATEQPAEQQRPELDIFK

Download         Length: 243 bp

>AT87603 NZ_CP024311:c421928-421686 [Rhizobium sp. NXC24]
ATGGACACCGCAAAAATCTTCTGGTCCGGCCGCTCGCAGGCCATACGCCTGCCAAAGGAATTTCGTCTCGACGGCGAAGA
AGTGCGCATCCGGCGGCAGGGAAAGGCAATCATTCTGGAGCCGATCGCCGAAGATTGGGATTGGCTGGAATCCGTTACAG
GGCCGGTCGACCACGATTTTGAAGAGGCGGCGACCGAACAGCCTGCCGAGCAGCAGCGCCCCGAACTGGATATCTTCAAG
TGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References