Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ParE-CopA/ParE-RHH
Location 224532..225097 Replicon chromosome
Accession NZ_CP024311
Organism Rhizobium sp. NXC24

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag NXC24_RS01095 Protein ID WP_104821614.1
Coordinates 224804..225097 (+) Length 98 a.a.

Antitoxin (Protein)


Gene name copA Uniprot ID -
Locus tag NXC24_RS01090 Protein ID WP_104821613.1
Coordinates 224532..224816 (+) Length 95 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NXC24_RS01070 219985..221622 + 1638 WP_104821609.1 ABC transporter ATP-binding protein -
NXC24_RS01075 221635..222594 + 960 WP_104821610.1 glyoxylate/hydroxypyruvate reductase A -
NXC24_RS01080 222672..222941 + 270 WP_158704412.1 hypothetical protein -
NXC24_RS01085 223140..224444 + 1305 WP_104821612.1 nicotinate phosphoribosyltransferase -
NXC24_RS01090 224532..224816 + 285 WP_104821613.1 CopG family transcriptional regulator Antitoxin
NXC24_RS01095 224804..225097 + 294 WP_104821614.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NXC24_RS01100 225109..226065 - 957 WP_104824943.1 hypothetical protein -
NXC24_RS01105 226239..228401 + 2163 WP_104821615.1 mechanosensitive ion channel family protein -
NXC24_RS01110 228499..229527 + 1029 WP_104821616.1 aldo/keto reductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-94)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 10960.65 Da        Isoelectric Point: 10.5026

>T87602 WP_104821614.1 NZ_CP024311:224804-225097 [Rhizobium sp. NXC24]
MPSVRLTQRALRDLERMRAFLRSKNAAAARKASARIIQTIQILSSQPDMGRPVEGSEQGLRELIVTFGRDGYIVLYQYIG
EDVLIAAIRHGREDGYK

Download         Length: 294 bp

>T87602 NZ_CP024311:224804-225097 [Rhizobium sp. NXC24]
ATGCCATCGGTAAGGCTGACGCAGCGCGCTCTTCGTGACCTCGAGCGGATGAGGGCATTTCTGCGGTCTAAAAATGCTGC
CGCGGCGAGGAAGGCATCAGCAAGGATTATTCAAACAATTCAGATATTGTCGAGCCAGCCCGATATGGGGCGGCCCGTGG
AAGGCTCAGAACAAGGATTACGCGAGCTCATCGTTACGTTTGGGCGGGATGGCTATATTGTTCTCTACCAATATATTGGT
GAGGACGTTCTTATAGCAGCCATCCGCCATGGCCGCGAAGATGGCTACAAGTAA

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 10888.04 Da        Isoelectric Point: 4.7881

>AT87602 WP_104821613.1 NZ_CP024311:224532-224816 [Rhizobium sp. NXC24]
MSPALKASVEIDPDVNERLEKLAASRHRHPNRLLNEAVRQYVEREEKRDSLLQDVRRSLDDYQATGLHVTGDEVIAWLET
WGDDDEKAPPECHR

Download         Length: 285 bp

>AT87602 NZ_CP024311:224532-224816 [Rhizobium sp. NXC24]
ATGTCACCCGCTTTGAAGGCCAGTGTAGAAATTGATCCTGACGTGAACGAGCGCCTGGAGAAGCTGGCTGCCAGTCGCCA
CCGTCACCCGAATCGGCTGCTGAACGAAGCCGTCAGGCAGTATGTGGAACGTGAGGAAAAGCGCGACTCTCTGTTGCAGG
ATGTGCGTCGTTCATTGGACGACTATCAGGCGACGGGCCTGCATGTGACGGGCGATGAAGTCATTGCTTGGTTAGAGACT
TGGGGCGACGACGATGAGAAGGCCCCACCTGAATGCCATCGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References