Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 1002610..1002881 | Replicon | chromosome |
| Accession | NZ_CP024289 | ||
| Organism | Escherichia coli O178:H19 strain 2012C-4431 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 1002740..1002843 (+) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 1002610..1002881 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| A5960_RS05230 | 999165..999827 | - | 663 | WP_000944256.1 | exodeoxyribonuclease X | - |
| A5960_RS05235 | 999851..1000507 | - | 657 | WP_000011658.1 | carbon-nitrogen hydrolase family protein | - |
| A5960_RS05240 | 1000609..1000839 | - | 231 | WP_000916763.1 | DNA polymerase III subunit theta | - |
| A5960_RS05245 | 1000978..1001352 | + | 375 | WP_000204699.1 | CopC domain-containing protein YobA | - |
| A5960_RS05250 | 1001356..1002228 | + | 873 | WP_099528345.1 | copper homeostasis membrane protein CopD | - |
| A5960_RS05255 | 1002241..1002582 | + | 342 | WP_000976472.1 | YebY family protein | - |
| - | 1002610..1002881 | - | 272 | - | - | Antitoxin |
| - | 1002740..1002843 | + | 104 | - | - | Toxin |
| A5960_RS05260 | 1002978..1003634 | + | 657 | WP_000812735.1 | protein-serine/threonine phosphatase | - |
| A5960_RS05265 | 1003635..1003826 | - | 192 | WP_001296140.1 | YebW family protein | - |
| A5960_RS05270 | 1003931..1004167 | - | 237 | WP_001295499.1 | DUF1480 family protein | - |
| A5960_RS05275 | 1004285..1005724 | - | 1440 | WP_001307251.1 | 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | stxA / stxB | 926505..1005730 | 79225 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 104 bp
>T87570 NZ_CP024289:1002740-1002843 [Escherichia coli O178:H19]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT
Antitoxin
Download Length: 272 bp
>AT87570 NZ_CP024289:c1002881-1002610 [Escherichia coli O178:H19]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
