Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2002565..2002836 Replicon chromosome
Accession NZ_CP024275
Organism Escherichia coli O6:H16 strain M9682-C1

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2002603..2002706 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2002565..2002836 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
COG40_RS10470 1999722..2001161 + 1440 WP_001397399.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
COG40_RS10475 2001279..2001515 + 237 WP_001338166.1 DUF1480 family protein -
COG40_RS10480 2001620..2001811 + 192 WP_001338167.1 YebW family protein -
COG40_RS10485 2001812..2002468 - 657 WP_000812732.1 protein-serine/threonine phosphatase -
- 2002565..2002836 + 272 - - Antitoxin
- 2002603..2002706 - 104 - - Toxin
COG40_RS10490 2002864..2003205 - 342 WP_000976472.1 YebY family protein -
COG40_RS10495 2003218..2004090 - 873 WP_000879295.1 copper homeostasis membrane protein CopD -
COG40_RS10500 2004094..2004468 - 375 WP_000168746.1 CopC domain-containing protein YobA -
COG40_RS10505 2004607..2004837 + 231 WP_000916763.1 DNA polymerase III subunit theta -
COG40_RS10510 2004939..2005595 + 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
COG40_RS10515 2005619..2006281 + 663 WP_000944258.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T87471 NZ_CP024275:c2002706-2002603 [Escherichia coli O6:H16]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT87471 NZ_CP024275:2002565-2002836 [Escherichia coli O6:H16]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References