Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1416271..1416542 Replicon chromosome
Accession NZ_CP024263
Organism Escherichia coli O169:H41 strain F6326-C1

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1416309..1416412 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1416271..1416542 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
COG38_RS07530 1413428..1414867 + 1440 WP_001718410.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
COG38_RS07535 1414985..1415221 + 237 WP_001295499.1 DUF1480 family protein -
COG38_RS07540 1415326..1415517 + 192 WP_001313035.1 YebW family protein -
COG38_RS07545 1415518..1416174 - 657 WP_001718411.1 protein-serine/threonine phosphatase -
- 1416271..1416542 + 272 - - Antitoxin
- 1416309..1416412 - 104 - - Toxin
COG38_RS07550 1416570..1416911 - 342 WP_000976472.1 YebY family protein -
COG38_RS07555 1416924..1417796 - 873 WP_001718412.1 copper homeostasis membrane protein CopD -
COG38_RS07560 1417800..1418174 - 375 WP_000168747.1 CopC domain-containing protein YobA -
COG38_RS07565 1418313..1418543 + 231 WP_000916763.1 DNA polymerase III subunit theta -
COG38_RS07570 1418645..1419301 + 657 WP_001718413.1 carbon-nitrogen hydrolase family protein -
COG38_RS07575 1419325..1419987 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T87373 NZ_CP024263:c1416412-1416309 [Escherichia coli O169:H41]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT87373 NZ_CP024263:1416271-1416542 [Escherichia coli O169:H41]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References