Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 4314507..4314778 Replicon chromosome
Accession NZ_CP024243
Organism Escherichia coli O128:H27 strain 90-9281

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 4314637..4314740 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 4314507..4314778 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
COG34_RS22340 4311062..4311724 - 663 WP_000944256.1 exodeoxyribonuclease X -
COG34_RS22345 4311748..4312404 - 657 WP_000011652.1 carbon-nitrogen hydrolase family protein -
COG34_RS22350 4312506..4312736 - 231 WP_000916763.1 DNA polymerase III subunit theta -
COG34_RS22355 4312875..4313249 + 375 WP_000204699.1 CopC domain-containing protein YobA -
COG34_RS22360 4313253..4314125 + 873 WP_000879282.1 copper homeostasis membrane protein CopD -
COG34_RS22365 4314138..4314479 + 342 WP_000976472.1 YebY family protein -
- 4314507..4314778 - 272 - - Antitoxin
- 4314637..4314740 + 104 - - Toxin
COG34_RS22370 4314875..4315531 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
COG34_RS22375 4315532..4315723 - 192 WP_001296140.1 YebW family protein -
COG34_RS22380 4315828..4316064 - 237 WP_001295499.1 DUF1480 family protein -
COG34_RS22385 4316182..4317621 - 1440 WP_001307251.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T87240 NZ_CP024243:4314637-4314740 [Escherichia coli O128:H27]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT87240 NZ_CP024243:c4314778-4314507 [Escherichia coli O128:H27]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References