Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 928701..928972 Replicon chromosome
Accession NZ_CP024240
Organism Escherichia coli O114:H49 strain 90-9280

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 928739..928842 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 928701..928972 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
COG33_RS05000 925858..927297 + 1440 WP_001352399.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
COG33_RS05005 927415..927651 + 237 WP_001295499.1 DUF1480 family protein -
COG33_RS05010 927756..927947 + 192 WP_001338167.1 YebW family protein -
COG33_RS05015 927948..928604 - 657 WP_000812723.1 protein-serine/threonine phosphatase -
- 928701..928972 + 272 - - Antitoxin
- 928739..928842 - 104 - - Toxin
COG33_RS05020 929000..929341 - 342 WP_000976492.1 YebY family protein -
COG33_RS05025 929354..930226 - 873 WP_000879280.1 copper homeostasis membrane protein CopD -
COG33_RS05030 930230..930604 - 375 WP_000168747.1 CopC domain-containing protein YobA -
COG33_RS05035 930743..930973 + 231 WP_000916763.1 DNA polymerase III subunit theta -
COG33_RS05040 931075..931731 + 657 WP_000011669.1 carbon-nitrogen hydrolase family protein -
COG33_RS05045 931755..932417 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T87199 NZ_CP024240:c928842-928739 [Escherichia coli O114:H49]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT87199 NZ_CP024240:928701-928972 [Escherichia coli O114:H49]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References