Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 300013..300284 Replicon chromosome
Accession NZ_CP024228
Organism Escherichia coli O25:NM strain 2014EL-1343-2

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 300143..300246 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 300013..300284 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
A3411_RS01575 296568..297230 - 663 WP_000944258.1 exodeoxyribonuclease X -
A3411_RS01580 297254..297910 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
A3411_RS01585 298012..298242 - 231 WP_000916763.1 DNA polymerase III subunit theta -
A3411_RS01590 298381..298755 + 375 WP_000168747.1 CopC domain-containing protein YobA -
A3411_RS01595 298759..299631 + 873 WP_000879295.1 copper homeostasis membrane protein CopD -
A3411_RS01600 299644..299985 + 342 WP_000976472.1 YebY family protein -
- 300013..300284 - 272 - - Antitoxin
- 300143..300246 + 104 - - Toxin
A3411_RS01605 300381..301037 + 657 WP_000812732.1 protein-serine/threonine phosphatase -
A3411_RS01610 301038..301229 - 192 WP_001338167.1 YebW family protein -
A3411_RS01615 301334..301570 - 237 WP_001338166.1 DUF1480 family protein -
A3411_RS01620 301688..303127 - 1440 WP_001397399.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T87117 NZ_CP024228:300143-300246 [Escherichia coli O25:NM]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT87117 NZ_CP024228:c300284-300013 [Escherichia coli O25:NM]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References