Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 1932097..1932242 | Replicon | chromosome |
| Accession | NZ_CP024191 | ||
| Organism | Klebsiella pneumoniae isolate KSB1_5D | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 1932133..1932235 (+) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 1932097..1932242 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| CS526_RS09610 | 1927227..1929287 | + | 2061 | WP_004151449.1 | oligopeptidase B | - |
| CS526_RS09615 | 1929291..1929950 | - | 660 | WP_032425085.1 | exodeoxyribonuclease X | - |
| CS526_RS09620 | 1930029..1930259 | - | 231 | WP_002911406.1 | DNA polymerase III subunit theta | - |
| CS526_RS09625 | 1930372..1930746 | + | 375 | WP_004151448.1 | CopC domain-containing protein YobA | - |
| CS526_RS09630 | 1930750..1931619 | + | 870 | WP_004189267.1 | copper homeostasis membrane protein CopD | - |
| CS526_RS09635 | 1931636..1931974 | + | 339 | WP_016529031.1 | YebY family protein | - |
| - | 1932097..1932242 | - | 146 | - | - | Antitoxin |
| - | 1932133..1932235 | + | 103 | - | - | Toxin |
| CS526_RS29855 | 1932610..1932753 | - | 144 | WP_002911398.1 | Ecr family regulatory small membrane protein | - |
| CS526_RS09645 | 1932858..1933826 | - | 969 | WP_004151446.1 | VirK/YbjX family protein | - |
| CS526_RS09650 | 1933983..1934636 | + | 654 | WP_004180432.1 | protein-serine/threonine phosphatase | - |
| CS526_RS09655 | 1934633..1934824 | - | 192 | WP_002911395.1 | YebW family protein | - |
| CS526_RS09660 | 1934922..1935161 | - | 240 | WP_002911393.1 | YebV family protein | - |
| CS526_RS09665 | 1935277..1936710 | - | 1434 | WP_032411854.1 | 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 103 bp
>T87064 NZ_CP024191:1932133-1932235 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
Antitoxin
Download Length: 146 bp
>AT87064 NZ_CP024191:c1932242-1932097 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
