87055

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pmenTA/darT(toxin)
Location 4875..6618 Replicon plasmid pYHS1
Accession NZ_CP024177
Organism Moraxella osloensis strain YHS

Toxin (Protein)


Gene name pmenT Uniprot ID -
Locus tag YHS_RS11430 Protein ID WP_099834540.1
Coordinates 4875..5525 (+) Length 217 a.a.

Antitoxin (Protein)


Gene name pmenA Uniprot ID -
Locus tag YHS_RS11435 Protein ID WP_099834541.1
Coordinates 5527..6618 (+) Length 364 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
YHS_RS11405 201..833 + 633 WP_099834538.1 AAA family ATPase -
YHS_RS11410 841..1059 + 219 WP_157797051.1 hypothetical protein -
YHS_RS11415 1274..4120 + 2847 WP_099834539.1 class I SAM-dependent DNA methyltransferase -
YHS_RS11420 4268..4558 + 291 WP_060996076.1 type II toxin-antitoxin system RelB/DinJ family antitoxin -
YHS_RS11425 4597..4824 + 228 WP_062335085.1 type II toxin-antitoxin system YafQ family toxin -
YHS_RS11430 4875..5525 + 651 WP_099834540.1 DUF4433 domain-containing protein Toxin
YHS_RS11435 5527..6618 + 1092 WP_099834541.1 macro domain-containing protein Antitoxin
YHS_RS11440 6761..8974 + 2214 WP_198510588.1 ATP-dependent helicase -
YHS_RS11445 8984..10357 + 1374 WP_099834542.1 GIY-YIG nuclease family protein -
YHS_RS11450 10682..11290 + 609 WP_099834589.1 recombinase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..105686 105686


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

ssDNA thymidine ADP-ribosyltransferase, DarT

(17-216)

Antitoxin

Macro domain

(18-138)


Sequences

Toxin        


Download         Length: 217 a.a.        Molecular weight: 25191.56 Da        Isoelectric Point: 7.1563

>T87055 WP_099834540.1 NZ_CP024177:4875-5525 [Moraxella osloensis]
MTYDYSNTLNPNKGLIWRIVHIANLPWIFANGLHSGNSPIQSPNWQHIGNPELIQKRANHPVPVGRQGYLNDYVPFYFTP
FSPMLLNIKSGRGVMQRPMQDILILVSSIDAVESQHLDYVFTNSHAYYQWTNFFTDKKDLDQIDWNLLQRRDFSRDPNDL
AKFERYQAEFLIYQHCPISAIIGICCYNDNVKQSIQQLINTSGITLDVHSRPNWYL

Download         Length: 651 bp

>T87055 NZ_CP024177:4875-5525 [Moraxella osloensis]
ATGACTTATGATTATAGTAATACATTAAACCCAAACAAAGGACTGATATGGCGGATTGTTCATATTGCGAACTTACCGTG
GATTTTTGCCAATGGCTTGCACAGTGGTAATAGCCCTATCCAATCACCTAATTGGCAACATATTGGTAATCCAGAACTGA
TTCAAAAACGAGCCAATCACCCTGTGCCTGTTGGACGGCAAGGTTATCTAAATGACTATGTGCCGTTTTATTTTACCCCT
TTTTCGCCCATGCTACTTAATATCAAATCGGGTCGGGGTGTGATGCAACGACCCATGCAAGATATCCTGATTTTGGTATC
ATCGATTGATGCGGTAGAAAGCCAGCATTTGGACTATGTTTTTACCAATAGCCATGCTTATTACCAATGGACAAACTTTT
TTACCGACAAAAAAGACCTAGACCAAATCGACTGGAATTTATTGCAACGCCGAGATTTTAGCCGTGACCCTAACGACTTG
GCAAAATTTGAGCGTTATCAAGCCGAATTTTTGATTTATCAGCATTGCCCCATATCGGCAATCATCGGTATCTGTTGTTA
TAATGATAACGTCAAACAAAGCATTCAACAATTAATCAATACGTCTGGCATTACATTGGACGTGCATAGCCGACCCAACT
GGTATCTTTAA

Antitoxin


Download         Length: 364 a.a.        Molecular weight: 41525.75 Da        Isoelectric Point: 6.4114

>AT87055 WP_099834541.1 NZ_CP024177:5527-6618 [Moraxella osloensis]
MITYTQGNLLEADTQALVNTVNTVGVMGKGIALMFKQQFPENFKRYAKACKSGDMQVGKMFVVAIDAPSIQHSQPQLKQR
WIVNFPTKQHWRAKSQIEWIQVGLQDLRQWLIDNRIESIAIPALGAGNGGLPWQQVKPLIEQTLGDLPNIDIQIFEPSGS
YYTVATAPITDNLTHARALLYQIVDRYWVLGMECSLLEVHKLMWFLQRAIERHRLANPLQLSFTPHYYGTYAPNLRHLLN
NLDGSYLLAEKRLPDCKPLDVIWTNQTKQAEVEQYLQTSMSDFLPVLTEVDNVIAGFESPFGLELLSTVDWLIYQEQYPA
TAEGIKQGMANWQAGEIWAKRKLELFNDQHIDIALQHLKTIYQ

Download         Length: 1092 bp

>AT87055 NZ_CP024177:5527-6618 [Moraxella osloensis]
ATGATTACATACACCCAAGGTAATTTGCTCGAAGCGGATACCCAAGCATTGGTTAACACCGTCAATACGGTCGGTGTGAT
GGGCAAAGGTATTGCATTAATGTTTAAACAACAATTTCCCGAAAATTTTAAACGCTATGCCAAAGCGTGCAAATCAGGTG
ATATGCAAGTCGGTAAAATGTTTGTGGTTGCCATTGATGCCCCATCTATACAACATTCTCAGCCCCAACTTAAGCAAAGA
TGGATAGTAAACTTTCCGACCAAACAGCATTGGCGAGCCAAATCACAAATCGAATGGATACAAGTAGGATTGCAAGATTT
GCGACAATGGTTAATTGATAATCGAATCGAATCGATAGCCATTCCCGCATTGGGGGCAGGTAATGGTGGACTACCTTGGC
AACAGGTAAAGCCACTGATTGAACAAACTTTGGGCGATTTGCCAAATATTGATATTCAAATCTTTGAACCATCGGGTAGT
TATTATACGGTCGCGACTGCACCAATAACTGATAATCTCACCCATGCTAGAGCCTTGTTGTATCAGATAGTTGACCGCTA
TTGGGTGCTTGGTATGGAATGTAGCTTGCTTGAAGTGCATAAACTGATGTGGTTTTTGCAACGAGCCATTGAGCGTCATC
GTCTAGCCAATCCGCTACAGCTATCATTTACGCCCCATTATTATGGTACTTATGCCCCAAATCTGCGTCATTTACTTAAC
AATCTAGATGGTAGCTATTTATTGGCTGAAAAGCGTCTGCCAGACTGCAAACCATTGGATGTTATTTGGACAAATCAAAC
TAAACAAGCTGAAGTTGAGCAATATTTGCAAACATCAATGTCAGATTTTTTACCCGTTTTGACAGAAGTTGATAATGTGA
TAGCAGGATTTGAGTCGCCGTTTGGCTTGGAGTTACTATCTACGGTGGATTGGCTAATCTATCAAGAACAATATCCTGCT
ACGGCGGAAGGTATTAAGCAAGGCATGGCAAATTGGCAAGCAGGGGAAATCTGGGCAAAACGTAAATTGGAATTATTCAA
TGACCAGCATATTGATATTGCATTACAACATTTGAAAACTATTTATCAGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References