Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2687616..2687887 Replicon chromosome
Accession NZ_CP024147
Organism Escherichia coli strain 14EC033

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2687654..2687757 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2687616..2687887 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CR539_RS13965 2684774..2686213 + 1440 WP_032281045.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
CR539_RS13970 2686330..2686566 + 237 WP_001295499.1 DUF1480 family protein -
CR539_RS13975 2686671..2686862 + 192 WP_001296140.1 YebW family protein -
CR539_RS13980 2686863..2687519 - 657 WP_032281033.1 protein-serine/threonine phosphatase -
- 2687616..2687887 + 272 - - Antitoxin
- 2687654..2687757 - 104 - - Toxin
CR539_RS13985 2687915..2688256 - 342 WP_000976472.1 YebY family protein -
CR539_RS13990 2688268..2689140 - 873 WP_000879287.1 copper homeostasis membrane protein CopD -
CR539_RS13995 2689144..2689518 - 375 WP_000168747.1 CopC domain-containing protein YobA -
CR539_RS14000 2689657..2689887 + 231 WP_000916763.1 DNA polymerase III subunit theta -
CR539_RS14005 2689989..2690645 + 657 WP_000011660.1 carbon-nitrogen hydrolase family protein -
CR539_RS14010 2690669..2691331 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T86954 NZ_CP024147:c2687757-2687654 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT86954 NZ_CP024147:2687616-2687887 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References