Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2128224..2128495 Replicon chromosome
Accession NZ_CP024141
Organism Escherichia coli strain 14EC029

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2128354..2128457 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2128224..2128495 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CR538_RS11130 2124779..2125441 - 663 WP_000944256.1 exodeoxyribonuclease X -
CR538_RS11135 2125465..2126121 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
CR538_RS11140 2126223..2126453 - 231 WP_000916763.1 DNA polymerase III subunit theta -
CR538_RS11145 2126592..2126966 + 375 WP_000204699.1 CopC domain-containing protein YobA -
CR538_RS11150 2126970..2127842 + 873 WP_000879334.1 copper homeostasis membrane protein CopD -
CR538_RS11155 2127855..2128196 + 342 WP_000976492.1 YebY family protein -
- 2128224..2128495 - 272 - - Antitoxin
- 2128354..2128457 + 104 - - Toxin
CR538_RS11160 2128592..2129248 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
CR538_RS11165 2129249..2129440 - 192 WP_001296140.1 YebW family protein -
CR538_RS11170 2129545..2129781 - 237 WP_001295499.1 DUF1480 family protein -
CR538_RS11175 2129899..2131338 - 1440 WP_000057024.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T86919 NZ_CP024141:2128354-2128457 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT86919 NZ_CP024141:c2128495-2128224 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References