Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2131231..2131502 Replicon chromosome
Accession NZ_CP024127
Organism Escherichia coli strain 14EC001

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2131361..2131464 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2131231..2131502 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CR534_RS11255 2127786..2128448 - 663 WP_000944256.1 exodeoxyribonuclease X -
CR534_RS11260 2128472..2129128 - 657 WP_000011657.1 carbon-nitrogen hydrolase family protein -
CR534_RS11265 2129230..2129460 - 231 WP_000916763.1 DNA polymerase III subunit theta -
CR534_RS11270 2129599..2129973 + 375 WP_024238488.1 CopC domain-containing protein YobA -
CR534_RS11275 2129977..2130849 + 873 WP_000879298.1 copper homeostasis membrane protein CopD -
CR534_RS11280 2130862..2131203 + 342 WP_000976472.1 YebY family protein -
- 2131231..2131502 - 272 - - Antitoxin
- 2131361..2131464 + 104 - - Toxin
CR534_RS11285 2131599..2132255 + 657 WP_000812733.1 protein-serine/threonine phosphatase -
CR534_RS11290 2132256..2132447 - 192 WP_001338167.1 YebW family protein -
CR534_RS11295 2132552..2132788 - 237 WP_001338166.1 DUF1480 family protein -
CR534_RS11300 2132906..2134345 - 1440 WP_024238487.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T86787 NZ_CP024127:2131361-2131464 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT86787 NZ_CP024127:c2131502-2131231 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References