Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1988051..1988322 Replicon chromosome
Accession NZ_CP024090
Organism Escherichia coli strain WG5

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1988181..1988284 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1988051..1988322 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CSR56_RS10015 1984606..1985268 - 663 WP_000944258.1 exodeoxyribonuclease X -
CSR56_RS10020 1985292..1985948 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
CSR56_RS10025 1986050..1986280 - 231 WP_000916763.1 DNA polymerase III subunit theta -
CSR56_RS10030 1986419..1986793 + 375 WP_000168747.1 CopC domain-containing protein YobA -
CSR56_RS10035 1986797..1987669 + 873 WP_000879295.1 copper homeostasis membrane protein CopD -
CSR56_RS10040 1987682..1988023 + 342 WP_000976472.1 YebY family protein -
- 1988051..1988322 - 272 - - Antitoxin
- 1988181..1988284 + 104 - - Toxin
CSR56_RS10045 1988419..1989075 + 657 WP_000812732.1 protein-serine/threonine phosphatase -
CSR56_RS10050 1989076..1989267 - 192 WP_001338167.1 YebW family protein -
CSR56_RS10055 1989372..1989608 - 237 WP_001338166.1 DUF1480 family protein -
CSR56_RS10060 1989726..1991165 - 1440 WP_001351758.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T86695 NZ_CP024090:1988181-1988284 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT86695 NZ_CP024090:c1988322-1988051 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References