Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 5378852..5379489 Replicon chromosome
Accession NZ_CP024085
Organism Pseudomonas putida strain E41

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag CR511_RS24305 Protein ID WP_099455410.1
Coordinates 5379082..5379489 (+) Length 136 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag CR511_RS24300 Protein ID WP_085272331.1
Coordinates 5378852..5379082 (+) Length 77 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CR511_RS24280 5374281..5375612 - 1332 WP_099455406.1 precorrin-3B synthase -
CR511_RS24285 5375745..5376956 + 1212 WP_099455407.1 precorrin-6y C5,15-methyltransferase (decarboxylating) subunit CbiE -
CR511_RS24290 5376949..5378043 + 1095 WP_099455408.1 cobalt-precorrin-5B (C(1))-methyltransferase -
CR511_RS24295 5378040..5378759 + 720 WP_099455409.1 cobalt-precorrin-6A reductase -
CR511_RS24300 5378852..5379082 + 231 WP_085272331.1 antitoxin Antitoxin
CR511_RS24305 5379082..5379489 + 408 WP_099455410.1 tRNA(fMet)-specific endonuclease VapC Toxin
CR511_RS24310 5379624..5380061 + 438 WP_099455411.1 NfeD family protein -
CR511_RS24315 5380088..5380942 + 855 WP_027592579.1 SPFH/Band 7/PHB domain protein -
CR511_RS24320 5381065..5381454 + 390 WP_099455412.1 DUF2946 domain-containing protein -
CR511_RS24325 5381501..5381986 + 486 WP_099455413.1 copper chaperone PCu(A)C -
CR511_RS24330 5382010..5382441 + 432 WP_099455414.1 DUF2946 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-124)

Antitoxin

SpoVT-AbrB domain

(7-56)


Sequences

Toxin        


Download         Length: 136 a.a.        Molecular weight: 15199.37 Da        Isoelectric Point: 7.0618

>T86684 WP_099455410.1 NZ_CP024085:5379082-5379489 [Pseudomonas putida]
MLRYLLDTNICIFTIKNKPQRVREAFNRHHGQLAISTITLMELIYGAEKSDHPERNLSVVEGFAARIEVLDYDSHAAEHS
GQLRAELARSGTPIGPYDQLIAGHARALGLILVTNNVREFQRVPGLRVEDWLVSP

Download         Length: 408 bp

>T86684 NZ_CP024085:5379082-5379489 [Pseudomonas putida]
ATGCTCAGGTACCTGCTCGACACCAATATCTGCATTTTCACGATCAAGAATAAACCGCAACGTGTCCGCGAAGCGTTCAA
TCGCCATCACGGTCAATTGGCGATCAGCACAATTACTTTGATGGAACTGATCTACGGCGCTGAGAAGTCGGATCATCCTG
AGCGCAATCTTTCGGTGGTCGAGGGCTTTGCCGCGCGCATTGAAGTACTCGATTACGATAGCCATGCGGCTGAGCACAGT
GGCCAGCTTCGTGCGGAATTGGCCAGATCAGGGACCCCCATTGGTCCTTACGACCAACTGATTGCCGGGCATGCCCGAGC
GCTTGGCTTAATTTTGGTGACTAACAATGTGCGCGAGTTTCAACGAGTACCAGGTCTAAGGGTTGAAGACTGGCTCGTTT
CGCCCTGA

Antitoxin


Download         Length: 77 a.a.        Molecular weight: 8397.32 Da        Isoelectric Point: 4.5045

>AT86684 WP_085272331.1 NZ_CP024085:5378852-5379082 [Pseudomonas putida]
MEQGAVFKSNRSQAIRLPKSVALPDGITRVDIVAVGRTRIITPAGESWDSWFESEPASADYMASRDQPADQEREGF

Download         Length: 231 bp

>AT86684 NZ_CP024085:5378852-5379082 [Pseudomonas putida]
ATGGAGCAAGGTGCTGTCTTCAAAAGCAACCGCAGCCAGGCCATCCGCTTGCCAAAATCCGTCGCACTTCCCGATGGCAT
CACCCGAGTGGATATTGTTGCAGTTGGGCGTACGCGCATCATCACACCTGCTGGTGAATCATGGGACAGCTGGTTCGAAA
GTGAGCCTGCAAGCGCGGATTACATGGCCAGCCGTGACCAACCTGCAGACCAGGAACGTGAAGGTTTTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References