86680

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tad-ata/COG5606-COG4679
Location 1098716..1099400 Replicon chromosome
Accession NZ_CP024085
Organism Pseudomonas putida strain E41

Toxin (Protein)


Gene name tad Uniprot ID -
Locus tag CR511_RS04935 Protein ID WP_099452998.1
Coordinates 1099029..1099400 (-) Length 124 a.a.

Antitoxin (Protein)


Gene name ata Uniprot ID -
Locus tag CR511_RS04930 Protein ID WP_099452997.1
Coordinates 1098716..1099036 (-) Length 107 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CR511_RS04905 1094881..1095282 + 402 WP_099452992.1 FagA protein -
CR511_RS04910 1095275..1096651 + 1377 WP_099452993.1 class II fumarate hydratase -
CR511_RS04915 1096701..1097162 + 462 WP_099452994.1 hypothetical protein -
CR511_RS04920 1097164..1097775 + 612 WP_099452995.1 superoxide dismutase -
CR511_RS04925 1097787..1098680 + 894 WP_099452996.1 ZIP family metal transporter -
CR511_RS04930 1098716..1099036 - 321 WP_099452997.1 helix-turn-helix domain-containing protein Antitoxin
CR511_RS04935 1099029..1099400 - 372 WP_099452998.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
CR511_RS04940 1099488..1099760 - 273 WP_027595603.1 HPr family phosphocarrier protein -
CR511_RS04945 1099781..1100635 - 855 WP_099452999.1 RNase adapter RapZ -
CR511_RS04950 1100638..1101102 - 465 WP_099453000.1 PTS IIA-like nitrogen regulatory protein PtsN -
CR511_RS04955 1101115..1101423 - 309 WP_003255135.1 ribosome-associated translation inhibitor RaiA -
CR511_RS04960 1101503..1102996 - 1494 WP_099453001.1 RNA polymerase factor sigma-54 -
CR511_RS04965 1103172..1103897 - 726 WP_027595607.1 LPS export ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(18-111)

Antitoxin

HigA2-like, helix-turn-helix domain

(11-90)


Sequences

Toxin        


Download         Length: 124 a.a.        Molecular weight: 13492.40 Da        Isoelectric Point: 9.4137

>T86680 WP_099452998.1 NZ_CP024085:c1099400-1099029 [Pseudomonas putida]
MDAFKRVKPLYWVGSSKKDLQEAPSDVQDIFGFALHLAQEGGKHPQAKCLKGFTGAGVLEVVENHDSDTYRAIYTVSLGA
AVYVLHCFQKKSNSGIKTPKHELDLIKSRLKQAAAHAKGTTHD

Download         Length: 372 bp

>T86680 NZ_CP024085:c1099400-1099029 [Pseudomonas putida]
ATGGATGCATTCAAACGTGTCAAACCGCTGTACTGGGTAGGAAGTAGCAAGAAGGATCTGCAGGAAGCGCCAAGCGATGT
ACAGGATATTTTCGGCTTTGCCCTGCATTTGGCACAAGAAGGGGGCAAACACCCTCAGGCGAAATGCCTGAAGGGCTTCA
CCGGTGCTGGCGTTCTGGAGGTGGTGGAAAACCACGACAGTGACACCTATCGCGCCATCTATACCGTAAGCCTGGGGGCT
GCGGTGTACGTCCTGCATTGTTTCCAGAAAAAATCCAATTCAGGCATCAAGACACCCAAGCACGAATTGGACTTGATCAA
GTCAAGGCTGAAGCAGGCAGCGGCTCACGCAAAAGGAACAACACATGATTGA

Antitoxin


Download         Length: 107 a.a.        Molecular weight: 11635.67 Da        Isoelectric Point: 9.8520

>AT86680 WP_099452997.1 NZ_CP024085:c1099036-1098716 [Pseudomonas putida]
MIEIEESSGNVYADLNSADAGEMLIKAHLASKICSIIKARHLTQVQAAAVLGLPQPKVSEMMRGKFRGISETKMIDCLAR
LGRDIQIVVKAAPRSRREGRVEVIFT

Download         Length: 321 bp

>AT86680 NZ_CP024085:c1099036-1098716 [Pseudomonas putida]
ATGATTGAGATCGAAGAAAGCAGCGGAAACGTCTATGCCGACCTCAACAGCGCAGACGCTGGCGAAATGCTGATAAAGGC
ACACCTGGCCAGCAAGATCTGCAGCATCATCAAGGCACGCCACCTGACTCAAGTGCAGGCAGCGGCAGTACTGGGGCTTC
CGCAACCCAAAGTCTCCGAAATGATGCGAGGGAAGTTTCGCGGTATCAGCGAGACAAAAATGATTGATTGCCTGGCACGC
CTTGGCCGCGACATTCAGATTGTGGTCAAGGCGGCGCCTCGCTCACGACGCGAGGGCCGGGTAGAAGTTATCTTCACCTG
A

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References